| Document Type
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BL
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| Record Number
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1001479
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| Doc. No
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b755849
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| Title & Author
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T cell regulation in allergy, asthma and atopic skin diseases /\ volume editor, Kurt Blaser.
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| Publication Statement
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Basel, Switzerland :: Karger,, ©2008.
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| Series Statement
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Chemical immunology and allergy,; v. 94
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| Page. NO
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1 online resource (xv, 225 pages) :: illustrations (some color).
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| ISBN
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3805586299
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: 9783805586290
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3805586280
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9783805586283
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| Bibliographies/Indexes
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Includes bibliographical references and indexes.
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| Contents
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Cover; Contents; Preface: Role of T-Cell Subtypes in Allergic Inflammations; Th17 and Treg Cells Innovate the Th1/Th2 Concept and Allergy Research; Abstract; General Role of T Cells in the Immune System; Treg Cells and Their Importance in Allergy; Th17 Cells -- Proinflammatory Cousins of Treg Cells?; Origin of T-Cell Phenotypes; Future and Perspective; Acknowledgements; References; Regulatory T Cells and Antigen-Specific Tolerance; Abstract; Characteristics of Regulatory T Cells; Intra- and Extrathymic Generation of Tregs; Function of Tregs; Concluding Remarks; References.
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Dendritic Cells and Regulatory T CellsMaturation Status of Dendritic Cells Is Critical for Induction of Regulatory T Cells; Regulatory T Cells Suppress DC Maturation; Monocytes/Macrophages and Regulatory T Cells; B Cells and Regulatory T Cells; Interaction between DCs and Regulatory T Cells during Allergic and Inflammatory Reactions; Conclusion; References; Mucosal Regulatory T Cells in Airway Hyperresponsiveness; Abstract; Respiratory Tolerance; Asthma; Measuring AHR; AHR in Asthma; Studying AHR in Animal Models; Inhibiting AHR in Animal Models; Treg Populations.
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Mast Cells Initiate and Modulate T-Cell Responses during Allergic Airway InflammationNovel and Distinct Roles for Basophils in Allergy; Conclusion; Acknowledgements; References; Regulatory Effects of Histamine and Histamine Receptor Expression in Human Allergic Immune Responses; Abstract; Molecular Basis for Action; Histamine Receptors; Synthesis and Metabolism of Histamine; Histamine in Chronic Inflammatory Responses; Role of Histamine in the Regulation of Immune Response; Antigen-Presenting Cells; Effect of Histamine on T Cells and Antibody Isotypes.
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Molecular Mechanisms of Regulatory T-Cell DevelopmentAbstract; Role of Foxp3 in TR Cell Function; Molecular Mechanisms of nTR Cell Development in the Thymus; Function of Foxp3 in nTR Cell Development; Transcriptional Regulation by Foxp3; The Foxp3 Transcriptional Program and the TR Cell Transcriptosome; Transcriptional Regulation of Foxp3; nTR versus iTR Cells; Heritable Disorders of TR Cells; TR Cell-Directed Therapeutic Interventions in Allergy and Autoimmunity; Concluding Remarks; References; Interaction of Regulatory T Cells with Antigen-Presenting Cells in Health and Disease; Abstract.
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Role of Treg in Inhibiting AHRRole of Treg in Human AHR; Therapeutic Means of Inhibiting AHR in Asthma; Conclusions; References; Natural Killer Cells in Allergic Inflammation; Abstract; Human Natural Killer Cell Subtypes; Lysis by NK Cells; NK Cells and Cytokines; NK Cells in Allergy; Concluding Remarks; References; Mast Cells and Mast Cell-Derived Factors in the Regulation of Allergic Sensitization; Abstract; Skin Models Implicate a Role for Mast Cells in Priming of Adaptive Immune Responses and Allergic Sensitization.
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| Abstract
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Important new findings for the development of novel allergy treatments.
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| Subject
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Allergy-- Immunological aspects.
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Asthma-- Immunological aspects.
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Skin-- Diseases-- Immunological aspects.
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T cells.
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Allergy-- Immunological aspects.
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HEALTH FITNESS-- Allergies.
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HEALTH FITNESS-- Diseases-- Immune System.
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MEDICAL-- Immunology.
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Skin-- Diseases-- Immunological aspects.
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T cells.
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T-Lymphocytes-- immunology.
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Asthma-- immunology.
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Hypersensitivity-- immunology.
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Skin Diseases-- immunology.
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| Dewey Classification
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616.97
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| LC Classification
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QR188.T2 2008eb
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| Added Entry
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Blaser, Kurt.
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| Added Entry
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S. Karger (Firm)
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