| Document Type
|
:
|
BL
|
| Record Number
|
:
|
1002476
|
| Doc. No
|
:
|
b756846
|
| Title & Author
|
:
|
Oxygen/nitrogen radicals : : lung injury and disease /\ edited by Val Vallyathan, Xianglin Shi, Vincent Castranova.
|
| Publication Statement
|
:
|
New York :: Marcel Dekker, Inc.,, ©2004.
|
| Series Statement
|
:
|
Lung biology in health and disease ;; v. 187
|
| Page. NO
|
:
|
xvii, 529 pages :: illustrations ;; 24 cm.
|
| ISBN
|
:
|
0824748743
|
|
|
:
|
: 9780824748746
|
| Bibliographies/Indexes
|
:
|
Includes bibliographical references and index.
|
| Contents
|
:
|
1. Reactive oxygen/nitrogen species : generation and reactions in the lung -- 2. Oxidative stress/antioxidant status in health and disease -- 3. Reactive oxygen species in the activation and regulation of intracellular signaling events -- 4. Mediators of lung inflammation : role of reactive oxygen and nitrogen species -- 5. Pulmonary complications of chronic granulomatous disease -- 6. Genotoxic and carcinogenic mechanisms of mineral fibers : role of reactive oxygen species -- 7. Influence of mineral dust surface characteristics and generation of reactive species -- 8. Oxygen/nitrogen radicals and silica-induced diseases -- 9. Asbestosis and asbestos-related cancers : role of reactive oxygen and nitrogen species -- 10. Interactions of exogenous or evoked reactive oxygen species and inhaled particles in the lung -- 11. Smoking-induced inflammation, injury and disease : molecular mechanisms -- 12. Respiratory health effects of ambient air pollution particles : role of reactive species -- 13. Ozone-induced lung injury : role of macrophages and inflammatory mediators -- 14. Oxidative stress in chronic obstructive pulmonary disease -- 15. Chronic obstructive pulmonary disease : mechanisms of disease development and prevention strategies with antioxidants -- 16. Acute respiratory distress syndrome and oxidative stress : mechanisms of disease development and opportunities for antioxidant prevention -- 17. Asthma and oxidative stress -- 18. Cellular responses of the lungs to hyperoxia -- 19. Vanadium and chromium-induced cell signal transduction -- 20. Molecular mechanisms of oxidant-induced pulmonary carcinogenesis.
|
| Abstract
|
:
|
(Publisher-supplied data) The first state-of-the-art book dealing specifically with lung injury induced by oxygen and nitrogen radicals, this detailed treatise discusses molecular, cellular, and mechanistic events leading to pathophysiological outcomes; the role of oxidant species in the induction of these events; and potential therapeutic avenues targeting such molecular pathways. Important issues regarding oxidative stress involvement in the initiation and progression of pulmonary diseases-including diseases caused by occupational and environmental inhalation of toxicants-are discussed in the context of amelioration by antioxidants.
|
| Subject
|
:
|
Active nitrogen-- Pathophysiology.
|
| Subject
|
:
|
Active oxygen-- Pathophysiology.
|
| Subject
|
:
|
Free radicals (Chemistry)-- Pathophysiology.
|
| Subject
|
:
|
Lungs-- Pathophysiology.
|
| Subject
|
:
|
Active oxygen-- Pathophysiology.
|
| Subject
|
:
|
Doenças respiratórias.
|
| Subject
|
:
|
Free radicals (Chemistry)-- Pathophysiology.
|
| Subject
|
:
|
Lungs-- Pathophysiology.
|
| Subject
|
:
|
Oxygène actif dans l'organisme.
|
| Subject
|
:
|
Pulmão (fisiopatologia)
|
| Subject
|
:
|
Radicais livres (fisiopatologia)
|
| Subject
|
:
|
Lung Diseases-- etiology.
|
| Subject
|
:
|
Lung Diseases-- physiopathology.
|
| Subject
|
:
|
Espèces réactives azotées.
|
| Subject
|
:
|
Espèces réactives oxygénées.
|
| Subject
|
:
|
Radicaux libres-- toxicité.
|
| Subject
|
:
|
Stress oxydatif.
|
| Subject
|
:
|
Free Radicals-- toxicity.
|
| Subject
|
:
|
Oxidative Stress-- physiology.
|
| Subject
|
:
|
Reactive Nitrogen Species-- physiology.
|
| Subject
|
:
|
Reactive Nitrogen Species-- toxicity.
|
| Subject
|
:
|
Reactive Oxygen Species-- toxicity.
|
| Dewey Classification
|
:
|
616.2/407
|
| LC Classification
|
:
|
RC756.O95 2004
|
| NLM classification
|
:
|
W1LU62 v.187 2004
|
|
|
:
|
WF 600
|
| Added Entry
|
:
|
Castranova, Vincent.
|
|
|
:
|
Shi, Xianglin,Ph. D.
|
|
|
:
|
Vallyathan, Val.
|