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" The ubiquitin-proteasome proteolytic system : "
editors, Aaron J. Ciechanover, Maria G. Masucci.
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BL
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| Record Number
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1004828
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b759198
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| Title & Author
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The ubiquitin-proteasome proteolytic system : : from classical biochemistry to human diseases /\ editors, Aaron J. Ciechanover, Maria G. Masucci.
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| Publication Statement
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New Jersey :: World Scientific,, ©2002.
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| Series Statement
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Recent advances in human biology ;; v. 9
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| Page. NO
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1 online resource (xx, 220 pages) :: illustrations (some color).
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| ISBN
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9789812381002
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: 9789812776877
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: 9812381007
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: 9812776877
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9812381007
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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The ubiquitin system and some of its roles in cell cycle control / A. Hershko -- The ubiquitin system and the N-end rule pathway / A. Varshavsky -- Phosphorylation-dependent substrate recognition in ubiquitin-mediated proteolysis / M. Tyers, P. Klein and T. Pawson -- The 26S proteasome: a supramolecular assembly designed for controlled proteolysis / W. Baumeister and P. Zwickl -- Mechanisms and regulation of ubiquitin-mediated, limited processing of the NF-[symbol] precursor protein p105 / A. Ciechanover [and others] -- Regulation of receptor tyrosine kinases by ubiquitination / A. Citri and Y. Yarden -- Regulation of p27 degradation / J. Bloom and M. Pagano -- Ubiquitin system-dependent regulation of growth hormone receptor signal transduction and effects of oxidative stress / C.M. Alves dos Santos and G.J. Strous -- Inhibition of the ubiquitin-proteasome system by a viral repetitive sequence / N.P. Dantuma and M.G. Masucci -- Autosomal recessive juvenile Parkinsonism and the ubiquitin pathway / K. Tanaka [and others].
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| Abstract
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Annotation Ubiquitin-proteosome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory.
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| Subject
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Proteins-- Metabolism.
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Proteolytic enzymes.
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Ubiquitin.
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MEDICAL-- Biochemistry.
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Proteins-- Metabolism.
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Proteolytic enzymes.
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Ubiquitin.
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| Dewey Classification
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612/.01575
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| LC Classification
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QP552.U24U257 2002eb
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| Added Entry
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Ciechanover, Aaron J.
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Masucci, Maria G.
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