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" Glycoscience and microbial adhesion / "
edited by Thisbe K. Lindhorst, Stefan Oscarson.
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BL
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| Record Number
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1008620
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| Doc. No
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b762990
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| Title & Author
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Glycoscience and microbial adhesion /\ edited by Thisbe K. Lindhorst, Stefan Oscarson.
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| Publication Statement
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Berlin ;London :: Springer,, 2009.
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| Series Statement
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Topics in current chemistry ;; 288
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| Page. NO
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1 online resource
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| ISBN
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1280382775
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: 3642013031
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: 364201304X
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: 6613560685
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: 9781280382772
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: 9783642013034
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: 9783642013041
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: 9786613560681
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Carbohydrate receptors of bacterial adhesins: Implications and reflections / K. Ohlsen [and others] -- Ins and outs of microbial adhesion / M. Virji -- Architectures of multivalent glycomimetics for probing carbohydrate-lectin interactions / M. Lahmann -- Structure, function, and assembly of type 1 fimbriae / S. Knight and J. Bouckaert -- The multiple carbohydrate binding specificities of helicobacter pylori / S. Teneberg -- Bitter sweetness of complexity / A. Horst and C. Wagener -- Staphylococcus epidermidis biofilms: Functional molecules, relation to virulence, and vaccine potential / D. Mack [and others].
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| Abstract
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Bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on ?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.
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| Subject
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Glycoconjugates.
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Microorganisms-- Adhesion.
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Adhäsion
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Chimie.
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Glycoconjugates.
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Glykokonjugate
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Kohlenhydrate
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Microorganisms-- Adhesion.
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Mikroorganismus
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Science des matériaux.
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Zelladhäsion
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Glycoconjugates.
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Microorganisms-- Adhesion.
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Bacterial Adhesion-- physiology.
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Adhesins, Bacterial.
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Glycocalyx-- metabolism.
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Glycosylation.
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| Dewey Classification
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572.567
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| LC Classification
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QP702.G577G59 2009
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| NLM classification
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QW 52G568 2009
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W1TO539LK v.288 2009
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Q936clc
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VA 1110rvk
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VK 8580rvk
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WD 5650rvk
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| Added Entry
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Lindhorst, Thisbe K.
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Oscarson, Stefan.
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