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" Aplastic anemia : "
edited by Hubert Schrezenmeier and Andrea Bacigalupo.
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BL
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| Record Number
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1012514
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b766884
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| Title & Author
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Aplastic anemia : : pathophysiology and treatment /\ edited by Hubert Schrezenmeier and Andrea Bacigalupo.
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| Publication Statement
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Cambridge, UK ;New York, NY :: Cambridge University Press,, 2000.
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1 online resource (xii, 391 pages) :: illustrations
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| ISBN
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0511017529
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: 0511036256
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: 0511117256
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: 0521641012
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: 9780511017520
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: 9780511036255
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: 9780511117251
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: 9780521641012
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0521641012
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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pt. I. Pathophysiology of acquired aplastic anemia. 1. Stem cell defect in aplastic anemia / Judith C.W. Marsh and Nydia G. Testa. 2. Cytokine abnormalities in aplastic anemia / Seiji Kojima. 3. Role of T-lymphocytes in the pathophysiology of aplastic anemia / Shinji Nakao. 4. Role of apoptosis in the pathophysiology of aplastic anemia / Frances M. Gibson, N.J. Philpott and Judith C.W. Marsh / [and others]. 5. The interrelation between aplastic anemia and paroxysmal nocturnal hemoglobinuria / Gerard Socie, Jean-Yves Mary and Hubert Schrezenmeier / [et al.]. 6. Aplastic anemia and other clonal disorders / Aruna Raghavachar -- pt. II. Epidemiology and clinical features of acquired aplastic anemia. 7. Epidemiology and etiology of aplastic anemia / Hermann Heimpel. 8. Clinical presentation, natural course, and prognostic factors / Pedro Marin-Fernandez -- pt. III. Treatment of acquired aplastic anemia. 9. Supportive treatment of patients with severe aplastic anemia / Per Ljungman.
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10. Immunosuppressive treatment of aplastic anemia / Andre Tichelli, Hubert Schrezenmeier and Andrea Bacigalupo. 11. Role of cytokines in the treatment of aplastic anemia / Hubert Schrezenmeier. 12. HLA-identical sibling bone marrow transplantation to treat severe aplastic anemia / Shaun R. McCann, Jakob R. Passweg and Rainer Storb / [and others]. 13. Alternative donor bone marrow transplantation for severe acquired aplastic anemia / Jill Hows, Judith Veum Stone and Bruce M. Camitta. 14. Treatment of children with acquired aplastic anemia / Anna Locasciulli. 15. Long-term follow-up of patients with aplastic anemia: clonal malignant and nonmalignant complications / Andre Tichelli and Gerard Socie. 16. Guidelines for treating aplastic anemia: Consensus Document of a group of international experts -- pt. IV. Fanconi's anemia. 17. Clinical features and diagnosis of Fanconi's anemia / Blanche P. Alter. 18. Genetic basis of Fanconi's anemia / Manuel Buchwald and Madeleine Carreau.
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| Abstract
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This book takes account of the most recent findings in laboratory research and clinical trials to provide a comprehensive and up-to-date reference on the pathophysiology, epidemiology, diagnosis and treatment of acquired and inherited aplastic anemia. As well as a detailed overview of the pathophysiology of the disease, the international team of authors cover all aspects of management, including the established approaches of bone marrow transplantation and immunosuppressive treatment, new approaches such as the use of hematopoietic growth factors and escalated immunosuppression, and controversial issues such as stem cell transplantation. Also included is an important international consensus document on treatment, and a final section concentrates on the inherited syndrome Fanconi's anemia. Detailed treatment guidelines are given, making this the definitive resource for hematologists and other clinicians involved in the management and supportive care of patients with aplastic anemia. Scientists interested in bone marrow failure will also find this an invaluable reference.
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| Subject
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Aplastic anemia.
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Anemia, Aplastic-- physiopathology.
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Anemia, Aplastic-- therapy.
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Aplastic anemia.
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MEDICAL-- Hematology.
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| Dewey Classification
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616.1/52
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| LC Classification
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RC641.7.A6A656 2000eb
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| NLM classification
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2000 F-127
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WH 175A6428 2000
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| Added Entry
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Bacigalupo, A.
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Schrezenmeier, H., (Hubert)
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