Document Type
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BL
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Record Number
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1020720
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Doc. No
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b775090
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Main Entry
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Panno, Joseph.
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Title & Author
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Gene therapy : : treating disease by repairing genes /\ Joseph Panno.
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Publication Statement
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New York, NY :: Facts On File,, ©2005.
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Series Statement
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Facts on File science library
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The "new biology" series
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Page. NO
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xvii, 172 pages :: illustrations ;; 23 cm.
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ISBN
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0816049483
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: 9780816049486
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Bibliographies/Indexes
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Includes bibliographical references (pages 151-155) and index.
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Contents
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Genetic disorders -- Immune deficiencies -- Breast cancer -- Colon cancer -- Melanoma -- Cystic fibrosis -- Hemophilia -- Liver disease -- Cardiovascular disease -- Muscular dystrophy -- Alzheimer's disease -- Parkinson's disease -- Huntington's disease -- Viruses: the cornerstone of gene therapy -- Viruses are living crystals -- Viral genomes may be RNA or DNA -- Viruses evolved from plasmids -- Viruses know how to infect cells -- The virus as a gene vehicle -- Viruses used in gene therapy -- Ashi DeSilva: a promising start -- Clinical trials defined -- Cells of the immune system -- Adenosine deaminase (ADA) -- Preliminary research -- Clinical procedure for ADA gene therapy -- The DeSilva clinical trial -- Jesse Gelsinger: down to earth -- Ornithine transcarbamylase (OTC) -- Preliminary research -- Clinical procedure for OTC gene therapy -- The Gelsinger clinical trial -- The investigation -- Concluding remarks -- Future prospects -- Safer vehicles -- Reducing immune rejection of the vector -- Improved risk assessment -- Redesigning human anatomy and physiology -- Ethics of gene therapy -- The Belmont report -- Clinical trials -- Physiological enhancement -- Cosmetic applications -- Legal issues -- Regulatory agencies -- The Gelsinger legal trial -- International regulation -- Resource center -- Eucaryote cell primer -- Recombinant DNA primer -- The human genome project -- X-linked severe combined immunodeficiency (SCID-X1) -- Alzheimer's disease (AD) -- Huntington's disease (HD).
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Abstract
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Discusses the science behind gene therapy, as well as the ethical and legal issues associated legal issues associated with this therapy.
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Subject
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Gene therapy.
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Subject
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Gene therapy.
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Subject
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Genetic Therapy.
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Dewey Classification
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615.8/95
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616.042
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LC Classification
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RB155.8.P36 2005
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NLM classification
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QZ50.P194g 2005
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QZ50.P194g 2005 9HUKM
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