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" Accelerating the development of biomarkers for drug safety : "
Steve Olson, Sally Robinson and Robert Giffin, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
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BL
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| Record Number
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1021213
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b775583
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| Title & Author
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Accelerating the development of biomarkers for drug safety : : workshop summary /\ Steve Olson, Sally Robinson and Robert Giffin, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
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| Publication Statement
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Washington, D.C. :: National Academies Press,, ©2009.
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1 online resource (xiv, 84 pages) :: illustrations
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| ISBN
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0309131243
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: 0309131251
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: 1282272659
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: 6612272651
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: 9780309131247
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: 9780309131254
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: 9781282272651
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: 9786612272653
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9780309131247
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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Introduction -- Overview Of key issues -- Cardiac safety biomarkers -- Assessing and predicting kidney safety -- Biomarkers of acute idiosyncratic hepatocellular injury in clinical trials -- Future considerations.
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| Abstract
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"Biomarkers can be defined as indicators of any biologic state, and they are central to the future of medicine. As the cost of developing drugs has risen in recent years, reducing the number of new drugs approved for use, biomarker development may be a way to cut costs, enhance safety, and provide a more focused and rational pathway to drug development. On October 24, 2008, the IOM's Forum on Drug Discovery, Development, and Translation held "Assessing and Accelerating Development of Biomarkers for Drug Safety," a one-day workshop, summarized in this volume, on the value of biomarkers in helping to determine drug safety during development."
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Biochemical markers, Congresses.
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Drugs-- Safety measures, Congresses.
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Drugs-- Testing, Congresses.
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Biochemical markers.
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Drugs-- Safety measures.
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Drugs-- Testing.
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MEDICAL-- Diagnosis.
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MEDICAL-- Laboratory Medicine.
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MEDICAL-- Nursing-- Assessment Diagnosis.
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Biological Markers, Congresses.
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Pharmaceutical Preparations-- adverse effects, Congresses.
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Drug Design, Congresses.
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Drug Discovery, Congresses.
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Drug Toxicity, Congresses.
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| Dewey Classification
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616.075
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| LC Classification
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R853.B54A23 2009eb
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| NLM classification
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2009 K-807
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QV 744I59c 2009
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| Added Entry
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Giffin, Robert B.
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Olson, Steve,1956-
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Robinson, Sally.
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Institute of Medicine (U.S.)., Forum on Drug Discovery, Development, and Translation.
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