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" Oral drug absorption : "
edited by Jennifer B. Dressman, Christos Reppas.
Document Type
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BL
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Record Number
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1021243
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Doc. No
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b775613
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Title & Author
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Oral drug absorption : : prediction and assessment /\ edited by Jennifer B. Dressman, Christos Reppas.
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Edition Statement
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2nd ed.
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Publication Statement
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New York :: Informa Healthcare,, ©2010.
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Series Statement
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Drugs and the pharmaceutical sciences ;; 193
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Page. NO
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1 online resource (xv, 413 pages) :: illustrations
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ISBN
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1420077341
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: 6612560924
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: 9781420077346
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: 9786612560927
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1420077333
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9781420077339
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Contents
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Physiology of oral drug absorption. Physiological factors affecting drug release and absorption in the gastrointestinal tract / Erik Söderlind and Jennifer B. Dressman -- Drug transport mechanisms across the intestinal epithelium / Anna-Lena B. Ungell -- Gastrointestinal transit and drug absorption / Clive G. Wilson, Werner Weitschies, and James Butler -- Gut wall metabolism / Mary F. Paine -- Food effects on drug absorption and dosage form performance / Anette Müllertz -- Oral drug absorption in pediatric populations / Andrea N. Edginton and Nikoletta Fotaki -- Gastrointestinal disease and dosage form performance / Vladan Milovic and Jürgen Stein -- The biopharmaceutics classification system. The biopharmaceutics classification system : recent applications in pharmaceutical discovery, development, and regulation / Jennifer J. Sheng and Gordon L. Amidon -- Drug solubility in the gastrointestinal tract / Christos Reppas and Patrick Augustijns -- Permeability measurement / Joachim Brouwers [and others] -- BCS : today and tomorrow / James E. Polli -- Nonclinical methods to evaluate oral formulations. Dissolution testing to forecast in vivo performance of immediate-release formulations / Ekarat Jantratid and Maria Vertzoni -- Dissolution testing to forecast the in vivo performance of MR formulations / Sandra Klein -- Modified-release dosage forms : formulation screening in the pharmaceutical industry / Bertil Abrahamsson and Erik Söderlind -- Immediate release oral dosage forms : formulation screening in the pharmaceutical industry / Yunhui Wu and Filippos Kesisoglou -- Computer models for predicting drug absorption / Neil Parrott and Thierry Lave -- Bioequivalence studies. In vivo bioequivalence assessment / Panos Macheras and Mira Symillides -- Biowaiving based on the BCS : a global comparision / Henrike Potthast -- Biowaiving based on in vitro-in vivo correlation / Vinod P. Shah.
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Abstract
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Examines the special equipment and methods used to test whether drugs are released adequately when administered orally.
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Subject
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Bioavailability.
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Subject
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Oral medication.
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Subject
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Bioavailability.
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Subject
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MEDICAL-- Pharmacology.
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Subject
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Oral medication.
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Subject
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Pharmaceutical Preparations-- metabolism.
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Subject
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Administration, Oral.
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Subject
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Biological Availability.
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Subject
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Solubility.
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Dewey Classification
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615/.6
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LC Classification
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RM162.O727 2010eb
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NLM classification
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QV 38O63 2010
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W1DR893B v.193 2010
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Added Entry
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Dressman, J. B., (Jennifer B.)
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Reppas, C., (Christos)
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