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BL
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| Record Number
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1025278
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| Doc. No
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b779648
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| Main Entry
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Serhan, Charles N.
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| Title & Author
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Fundamentals of Inflammation.
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| Publication Statement
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Cambridge :: Cambridge University Press,, 2010.
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| Page. NO
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1 online resource (489 pages)
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| ISBN
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0511725027
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: 0511727836
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: 1139195735
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: 9780511725029
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: 9780511727832
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: 9781139195737
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0511726449
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0521887291
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9780511726446
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9780521887298
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| Notes
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5 Mast Cells as Sentinels of Inflammation.
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Cover; Half-title; Title; Copyright; Contents; Contributors; Preface; Part I. The Inflammatory Response -- an Overview; 1 Acute and Chronic Inflammation; Introduction; The Acute Inflammatory Response; Regulation of the Acute Inflammatory Response; The Complement Cascade; Intercommunications between Inflammatory Cascades and the Coagulation Cascade; Outcomes of the Acute Inflammatory Response and Disordered Responses; Functional Consequences of the Acute Inflammatory Response; Granulomatosis Inflammation; Chronic Inflammation; Therapeutic Interventions in Inflammation; Acknowledgments.
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Immune RecognitionImmune Effectors; Immune Counter-Regulation; Relationship between Acute versus Chronic Inflammation and Innate versus Adaptive Immunity; Regulation of Adaptive Immunity by the Innate Immune System; Activation of Adaptive Immune responses: T Cells; Activation of adaptive Immune responses: B Cells; Immune Class Specification; Counter-regulation of Adaptive Immune Responses; Regulation of Innate Immunity by the Adaptive Immune System; Regulation of Innate Immune Cell Function; Counter-Regulation of Innate Immune Responses.
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Neutrophil Propagation of Inflammation: Production of Inflammatory MediatorsArachidonic Acid Metabolites; Cytokine Production; References; Suggested Readings; 4B Neutrophils II; Introduction; Neutrophil Differentiation, Maturation, and Other Generalities; Neutrophil Microbicidal Mechanisms; Neutrophil Receptors; The Role of Neutrophils in Acute Inflammation; Neutrophil-Derived Cytokines; Neutrophil Cross Talk With Other Cell Types: Role of Neutrophil-Derived Chemokines; Neutrophil Apoptosis; Neutrophils in Human Diseases; Conclusions; Suggested Readings.
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Suggested readings2 Resolution of Acute Inflammation and Wound Healing; Summary; Inflammation in Health and Disease; What is Inflammatory Resolution?; Soluble Mediators of Inflammation and Resolution; Controlling Onset; Onset to Resolution; Resolving Inflammation; Getting Rid of Leukocytes; Macrophages and Resolution -- Cellular Players and Homeostasis; Resolution of Adaptive Immune Responses; Wound Healing; Conclusion; Glossary of Terms; References; Suggested Readings; 3 Links between Innate and Adaptive Immunity; The innate and adaptive immune systems: definitions, context, and contrasts.
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Tissue-Specific Immunity: Organ-Specific Regulation of Immune ResponsesSuggested Readings; Part II. Individual Cell Types; 4A Neutrophils I; Introduction; Neutrophil Homeostasis: Myelopoiesis and Destruction; Neutrophil Anatomy: Morphology and Granules; Neutrophil Physiology: Activation and Function; Stimuli and Receptors; Intracellular Signaling and Second Messengers; Second Messengers; Kinases and Kinase Cascades; The Consequences of Neutrophil Activation: Adhesion, Migration, and Bacterial Killing; Neutrophil Adhesion and Migration; Phagocytosis and Bacterial Killing.
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| Abstract
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Provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion.
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| Subject
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Immunity, Cellular.
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Inflammation-- Immunological aspects.
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Inflammation.
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Immunity, Cellular-- physiology.
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| Subject
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Inflammation-- Immunological aspects.
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| Subject
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Inflammation.
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| Subject
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Inflammation-- immunology.
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| Dewey Classification
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571.964616.0473
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| LC Classification
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RB131
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| NLM classification
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2010 F-396
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QW 700F981 2010
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| Added Entry
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Ayoub, Samir S.
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Gilroy, Derek W.
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Ward, Peter A.
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