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" Drug metabolism concepts : "
Donald M. Jerina, editor.
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BL
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| Record Number
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1029277
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b783647
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| Title & Author
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Drug metabolism concepts : : a symposium cosponsored by the Division of Medicinal Chemistry and the division of Analytical Chemistry at the 172nd meeting of the American Chemical Society, San Francisco, Calif., August 31, 1976 : [Proceedings] /\ Donald M. Jerina, editor.
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| Publication Statement
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Washington :: American Chemical Society,, 1977.
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| Series Statement
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ACS symposium series ;; 44,
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| Page. NO
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ix, 196 pages :: illustrations ;; 24 cm.
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| ISBN
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0841203709
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: 9780841203709
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0841203547
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9780841203549
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Cytochrome P-450 : its role in oxygen activation for drug metabolism / R.W. Estabrook and J. Werringloer -- Synthetic models for the reaction stages of cytochrome P-450 / James P. Collman and Thomas N. Sorrell -- Biochemical studies on drug metabolism : isolation of multiple forms of liver microsomal cytochrome P-450 / M.J. Coon, J.L. Vermilion, K.P. Vatsis, J.S. French, W.L. Dean, and D.A. Haugen -- Resolution of multiple forms of rabbit liver cytochrome P-450 / Eric F. Johnson and Ursula Muller-Eberhard -- Enantiomeric selectivity and perturbation of product ratios as methods for studying the multiplicity of microsomal enzymes / William F. Trager -- Role of purified cytochrome P-448 and epoxide hydrase in the activation and detoxification of benzo[a]pyrene / W. Levin, A.W. Wood, A.Y.H. Lu, D. Ryan, S. West, A.H. Conney, D.R. Thakker, H. Yagi, and D.M. Jerina -- In vitro reactions of the diastereomeric 9,10-epoxides of (+) and ( -- )-trans-7,8-dihydroxy-7,8-dihydrobenzo-[a]pyrene with polyguanylic acid and evidence for formation of an enantiomer of each diastereomeric 9,10-epoxide from benzo[a]pyrene in mouse skin / P.D. Moore, M. Koreeda, P.G. Wislocki, W. Levin, A.H. Conney, H. Yagi, and D.M. Jerina -- Role of metabolic activation in chemical-induced tissue injury / Sidney D. Nelson, Michael R. Boyd, and Jerry R. Mitchell.
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| Subject
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Benzopyrene-- Metabolism, Congresses.
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Carcinogenesis, Congresses.
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Cytochrome P-450, Congresses.
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Drugs-- Metabolism, Congresses.
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Benzopyrene-- Metabolism.
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Carcinogenesis.
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Cytochrome P-450.
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Drugs-- Metabolism.
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Drug Synergism.
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Drug Tolerance.
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Metabolism-- drug effects.
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Pharmaceutical Preparations-- metabolism.
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| Dewey Classification
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615/.7
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| LC Classification
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RM301.D76
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| NLM classification
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QV 38D7936 1976
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35.79bcl
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44.38bcl
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| Added Entry
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Jerina, Donald M., (Donald Michael),1940-
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American Chemical Society., Division of Analytical Chemistry.
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American Chemical Society., Division of Medicinal Chemistry.
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