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" Experimental and applied immunotherapy / "
Jeffrey Medin, Daniel Fowler, editors.
Document Type
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BL
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Record Number
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1030993
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Doc. No
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b785363
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Title & Author
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Experimental and applied immunotherapy /\ Jeffrey Medin, Daniel Fowler, editors.
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Publication Statement
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New York :: Humana Press,, ©2011.
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Page. NO
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1 online resource (xvii, 442 pages) :: illustrations (some color)
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ISBN
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1607619806
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: 9781607619802
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1607619792
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9781607619796
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Contents
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T cell therapy: state-of-the-art -- Extending the use of adoptive T cell immunotherapy for infections and cancer -- Non-T cell therapeutic approaches -- B lymphocytes in cancer immunology -- Monoclonal antibody therapy for cancer -- Natural killer cells for cancer immunotherapy -- Dendritic cell-based cancer vaccines: practical considerations -- Mesenchymal stromal cells: an emerging cell-based pharmaceutical -- T cell therapeutic approaches -- Tumor-specific mutations as targets for cancer immunotherapy -- Counteracting subversion of MHC class II antigen presentation by tumors -- Mechanisms and implications of immunodominance in CD8 T-cell responses -- T regulatory cells and cancer immunotherapy -- Negative regulators in cancer immunology and immunotherapy -- Genetically engineered antigen specificity in T cells for adoptive immunotherapy -- Non-cellular aspects of cancer immunotherapy -- Cytokine immunotherapy -- Transcriptional modulation using histone deacetylase inhibitors for cancer immunotherapy -- Combining cancer vaccines with conventional therapies -- Combining oncolytic viruses with cancer immunotherapy -- Radiation therapy and cancer treatment: from the basics to combination therapies that ignite immunity -- Assessing immunotherapy through cellular and molecular imaging -- Transplantation -- Allogeneic and autologous transplantation therapy of cancer: converging themes.
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Abstract
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Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic.
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Subject
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Immunotherapy.
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Subject
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Cancer Vaccines-- therapeutic use.
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Subject
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Immunotherapy-- methods.
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Subject
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Neoplasms-- immunology.
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Subject
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Neoplasms-- therapy.
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Subject
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T-Lymphocytes-- immunology.
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Subject
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HEALTH FITNESS-- Diseases-- Cancer.
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Subject
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Immunotherapy.
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Subject
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MEDICAL-- Oncology.
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Dewey Classification
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616.07/9
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LC Classification
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RM275.E97 2011
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NLM classification
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2011 C-413
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QZ 266
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Added Entry
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Fowler, Daniel H.
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Medin, Jeffrey.
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