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" Targeted therapies in oncology / "
edited by Giuseppe Giaccone, Jean-Charles Soria.
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BL
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| Record Number
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1032958
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b787328
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| Title & Author
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Targeted therapies in oncology /\ edited by Giuseppe Giaccone, Jean-Charles Soria.
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| Publication Statement
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New York :: Informa Healthcare,, ©2007.
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| Page. NO
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ix, 412 pages :: illustrations ;; 24 cm
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| ISBN
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084939371X
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: 9780849393716
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Overview of existing therapies / Jiannis Mountzios and Jean-Charles Soria -- Signal transduction inhibitors, HER family, EGFR inhibition, and clinical achievements / Giuseppe Giaccone and Paolo Zucali -- HER2 inhibition and clinical achievements / Toru Mukohara and Pasi A. Jänne -- Pan-HER inhibitors / Gérard Milano -- Inhibiting the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway / Janet E. Dancey -- Farnesyl transferase inhibitors in cancer: promise, but limited proof / Laura Fanucchi, Michael P. Fanucchi, and Fadlo R. Khuri -- Protein Kinase C inhibitors in the treatment of non-small cell lung cancer / Yun Oh [and others] -- Signal transduction inhibitors: PDGFR and c-KIT inhibitors / Jean-Yves Blay [and others] -- The insulin-like growth factor 1 receptor: a target for cancer treatment / Yungan Tao, Jean Bourhis, and Eric Deutsch -- Aurora kinase inhibitors / Mitesh J. Borad, Steven L. Warner, and Daniel D. von Hoff -- Apoptosis modulators: p53 targeting / Sunil Chada [and others] -- Survivin / Dario C. Altieri -- TRAIL modulators / C.H. Mom [and others] -- VEGF targeting / Lee M. Ellis -- Targeting angiogenesis with oral agents / Benjamin Besse and Jean-Pierre Armand -- Endothelial cell propagation targteing / Gordon C. Tucker -- HIF-1 inhibitors / Giovanni Melillo -- Antivascular agents / Jane Robertson -- Matrix metalloproteinases / Stéphane Vignot and Jean-Philippe Sapno -- Src inhibitors / Francisco Cruzalegui -- Telomerase and Telomere interacting agents / Jean-Franc̦oi Riou [and others] -- Targeting Hsp90: the cancer super-chaperone / Paul Workman and Swee Sharp.
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| Abstract
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This book presents an authoritative overview of existing molecular targeted therapies, their relevance and role for specific tumors, and their clinical efficacy and impact on patient treatment.
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| Subject
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Cancer-- Treatment.
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Cancer-- Treatment.
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Neoplasms-- therapy.
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Genetic Therapy.
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Immunotherapy.
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| Dewey Classification
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616.99/406
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| LC Classification
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RC270.8.T37 2007
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| NLM classification
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2007 L-355
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QZ 266T1847 2007
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| Added Entry
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Giaccone, Giuseppe.
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Soria, Jean-Charles.
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