| Document Type
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BL
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| Record Number
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1033381
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| Doc. No
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b787751
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| Title & Author
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Drug design and discovery : : methods and protocols /\ edited by Seetharama D. Satyanarayanajois.
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| Publication Statement
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New York :: Humana Press,, ©2011.
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| Series Statement
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Methods in molecular biology ;; v. 716
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| Page. NO
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1 online resource (xi, 284 pages)
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| ISBN
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1617790125
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: 9781617790126
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1617790117
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9781617790119
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Abstract
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Research in the pharmaceutical sciences and medicinal chemistry has taken an important new direction in the past two decades with a focus on large molecules, especially peptides and proteins, as well as DNA therapeutics. In Drug Design and Discovery: Methods and Protocols, leading experts provide an in-depth view of key protocols that are commonly used in drug discovery laboratories. Covering both classic and cutting-edge techniques, this volume explores computational docking, quantitative structure-activity relationship (QSAR), peptide synthesis, labeling of peptides and proteins with fluorescent labels, DNA-microarray, zebrafish model for drug screening, and other analytical screening and biological assays that are routinely used during the drug discovery process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and accessible, Drug Design and Discovery: Methods and Protocols serve as a vital laboratory reference for pharmaceutical chemists, medicinal chemists, and pharmacologists as well as for molecular biologists.
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| Subject
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Drugs-- Design.
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Analytical, Diagnostic and Therapeutic Techniques and Equipment
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Biochemistry.
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Biological Science Disciplines.
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Biology.
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Chemistry, Pharmaceutical.
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Chemistry.
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Disciplines and Occupations
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Drug Design.
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Drug Discovery-- methods.
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Drug Discovery.
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Genetics.
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Investigative Techniques
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Methods.
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Molecular Biology.
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Natural Science Disciplines.
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Pharmacology.
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Health Biological Sciences.
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Pharmacy, Therapeutics, Pharmacology.
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| Subject
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Drugs-- Design.
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| Subject
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Health Biological Sciences.
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| Subject
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Pharmacy, Therapeutics, Pharmacology.
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| Dewey Classification
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615/.19
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| LC Classification
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RS420.D78 2011
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| NLM classification
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QV 744
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W1ME9616J v.716 2011
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| Added Entry
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Satyanarayanajois, Seetharama D.
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