| Document Type
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BL
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| Record Number
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1038429
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b792799
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| Title & Author
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Clinical trials in hypertension /\ edited by Henry R. Black.
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| Publication Statement
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New York :: Marcel Dekker,, ©2001.
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| Page. NO
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xi, 659 pages :: illustrations, maps ;; 26 cm
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| ISBN
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0824702700
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: 9780824702700
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Department of Veterans Affairs Cooperative Study on Monotherapy of Hypertension -- The Systolic Hypertension in Europe Trial -- Hypertension Optimal Treatment (HOT) Study -- Beta-blocker Heart Attack Trial -- Effect of enalapril on morbid and mortal events among SOLVD participants with hypertension -- Captopril in Type 1 Diabetic Nephropathy -- Attenuation of ventricular enlargement: The SAVE study -- STOP-Hypertensio-2: The Swedish Trial in Old Patients with Hypertension-2 -- The Controlled ONset Verapamil INvestigation of Cardiovascular Endpoints (CONVINCE) Trial -- Rationale and design for the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) -- The 2nd Australian National Blood Pressure Study (ANBP2) --Losartan Intervention for Endpoint Reduction in Hypertension: The LIFE Study -- Prospective collaborative overviews of major randomized trials of blood-pressure-lowering treatments.
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The Veterans Administration Cooperative Study on Antihypertensive Drugs -- The treatment of mild essential hypertension: The U.S. Public Health Service Hospitals Clinical Trial -- The Hypertension Detection and Follow-up Program -- The Australian National Blood Pressure Study 1973-1979 / Ralph Reader -- The MRC Trial of Treatment in Mild Hypertension -- Beta-blockers versus diuretics in hypertensive men: The HAPPHY Trial -- Metoprolol versus thiazide diuretics in hypertension: results from the MAPHY Study in perspective -- The European Working Party on High Blood Pressure in the Elderly (EWPHE) Trial -- The Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) -- Systolic Hypertension in the Elderly Program (SHEP): the first demonstration that lowering systolic hypertension reduced total stroke and all coronary heart disease -- Medical Research Council Trial of Treatment of Hypertension in Older Adults -- The Treatment of Mild Hypertension Study (TOMHS): design and additional analyses.
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| Abstract
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Compiling descriptions, results, and analyses from 24 complete or soon-to-be-complete influential clinical trials studying the efficacy of pharmacological therapy in hypertension, this detailed reference examines treatment for hypertension from a variety of perspectives, including trials sponsored by both international governments and pharmaceutical firms. Organized to facilitate convenient comparison and evaluation of results for therapeutic decisions, Clinical Trials in Hypertension: identifies objectives, inclusion/exclusion criteria, baseline characteristics of subjects, and drug regimens; spotlights trials that established the effectiveness of breakthrough treatments such as treating young hypertensives with diastolic blood pressure elevations; reviews numerous drug studies-including Heart Attack Primary Prevention in Hypertension (HAPPHY), Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY), and Treatment of Mild Hypertension Study (TOMHS)-contrasting diuretics, -adrenergic receptor blockers, angiotensin converting enzyme inhibitors, -adrenergic receptor blockers, and calcium antagonists; considers treatment options and results with older hypertensives; and more! Reports on the collaboration between the World Health Organization and the International Society of Hypertension pooling data from more than 30 clinical trials currently in progress.
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| Subject
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Clinical trials-- Evaluation-- History.
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Hypertension-- Chemotherapy-- Evaluation-- History.
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Hypotensive agents-- Testing-- History.
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Ätiologie
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Clinical trials-- Evaluation.
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Hypertonie
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Hypotensive agents-- Testing.
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Kontrollierte klinische Studie
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Therapie.
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Hypertension-- drug therapy.
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Antihypertensive Agents-- therapeutic use.
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Clinical Trials as Topic-- history.
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| Dewey Classification
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616.1/32061
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| LC Classification
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RC685.H8C565 2001
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| NLM classification
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2001 E-437
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WG 340C6417 2001
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YC 1415rvk
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| Added Entry
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Black, Henry R., (Henry Richard),1942-
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