| Document Type
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BL
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| Record Number
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1044363
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| Doc. No
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b798733
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| Main Entry
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Valentine, R. C., (Raymond Carlyle),1936-
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| Title & Author
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Omega-3 fatty acids and the DHA principle /\ Raymond C. Valentine, David L. Valentine.
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| Publication Statement
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Boca Raton, FL :: CRC Press,, ©2010.
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| Page. NO
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xix, 249 pages :: illustrations (some color) ;; 25 cm
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| ISBN
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1439812993
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: 9781439812990
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Ch. 1. Molecular biology of Omega-3 chains as structural lipids : many central questions remain unanswered -- Ch. 2. Darwinian selection of the fittest membrane lipids : from archaeal isoprenoids to DHA-enriched rhodopsin disks -- Ch. 3. Coevolution of DHA membranes and their proteins -- Ch. 4. Convergent evolution of DHA/EPA biosynthetic pathways -- Ch. 5. Membrane evolution in a marine bacterium : capitalizing on DHA for energy conservation in seawater -- Ch. 6. Evolution of DHA membranes in human neutrons -- Ch. 7. DHA/EPA chains as powerful membrane antifreeze -- Ch. 8. DHA as a mediocre permeability barrier against cations : water wire theory -- Ch. 9. DHA/EPA membranes as targets of oxidative damage -- Ch. 10. Bacteria : environmental modulation of membrane lipids for bioenergetic gain -- Ch. 11. Chloroplasts : harnessing DHA/EPA for harvesting light in the sea -- Ch. 12. Mitochondria : DHA-cardiolipin boosts energy output -- Ch. 13. Sperm : essential roles of DHA lead to development of a mechanical stress hypothesis -- Ch. 14. DHA/EPA mutualism between bacteria and marine animals -- Ch. 15. Membrane adaptations for an oily environment : lessons from a petroleum-degrading bacterium -- Ch. 16. Lessons from yeast : phospholipid conformations are important in winemaking -- Ch. 17. DHA principle applied to global warming -- Ch. 18. DHA principle applied to molecular farming -- Ch. 19. DHA/unsaturation theory of aging -- Ch. 20. DHA principle applied to neurodegenerative diseases -- Ch. 21. Dietary DHA in prevention of colon cancer : how a risk to the cell benefits the organism.
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| Abstract
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The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Exploring the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria, and develops a principle by which to assess their benefits and risks. This book lays the groundwork to understanding this code. It examines the evolution of DHA and the membrane and explores the general properties of omega-3s and other membrane lipids. It then focuses on cellular biology before shifting to a practical discussion on applications. The authors discuss the DHA Principle as applied to petroleum degradation, winemaking, global warming, mol.
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| Subject
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Docosahexaenoic acid-- Health aspects.
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| Subject
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Omega-3 fatty acids-- Health aspects.
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Omega-3 fatty acids-- Health aspects.
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Docosahexaenoic Acids-- metabolism.
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Docosahexaenoic Acids-- pharmacology.
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| Subject
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Membrane Lipids-- metabolism.
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| Dewey Classification
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612.3/97
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| LC Classification
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QP752.D63V35 2010
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| NLM classification
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2010 A-839
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QU 90V159o 2010
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| Added Entry
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Valentine, David L.
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