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" Systems biology in drug discovery and development : "
edited by Qing Yan.
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BL
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| Record Number
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1047234
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b801604
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| Title & Author
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Systems biology in drug discovery and development : : methods and protocols /\ edited by Qing Yan.
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| Publication Statement
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New York, N.Y. :: Humana Press,, ©2010.
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| Series Statement
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Methods in molecular biology,; v. 662
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Springer protocols
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| Page. NO
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1 online resource (xii, 337 pages) :: color illustrations
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| ISBN
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1607617994
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: 1607618001
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: 9781607617990
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: 9781607618003
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9781607617990
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Proteomics and systems biology : application in drug discovery and development / Bulbul Chakravarti, Buddhadeb Mallik, and Deb N. Chakravarti -- Systems biology aproaches and tools for analysis of interactomes and multi-target drugs / André Schrattenholz, Karlfried Groebe, and Vukic Soskic -- Systems biology "on the fly" : SILAC-based quantitative proteomics and RNAi apporach in Drosophila melanogaster / Alessandro Cuomo and Tiziana Bonaldi -- Systems biology of cell behavior / Najil V. Valeyev [and others] -- Computational modeling in systems biology / Ravishankar R. Vallabhajosyula and Alpan Raval -- An introduction to Gaussian Bayesian networks / Marco Grzegorczyk -- Derivation of large-scale cellular regulatory networks from biological time series data / Benjamin L. de Bivort -- Translational bioinformatics and systems biology approaches for personalized medicine / Qing Yan -- Systems biology and inflammation / Yoram Vodovotz and Gary An -- Immunoinformatics and systems biology methods for personalized medicine / Qing Yan -- Systems biology approaches to the study of cardiovascular drugs / Yuri Nikolsky and Robert Kleemann -- Cancer systems biology / Dana Faratian [and others] -- Systemic lubus erythematosus : from genes to organ damage / Vasileios C. Kyttaris -- Systems biology of influenza : understanding multidimensional interactions for personalized prevention and treatment / Qing Yan -- Methods in systems biology of experimental methamphetamine drug abuse / Firas H. Kobiessy [and others] -- Systems biology and theranostic approach to drug discovery and development to treat traumatic brain injury / Zhiqun Zhang [and others].
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| Abstract
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Due to the failing "one-drug-fits-all" model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology. series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.
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| Subject
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Drug development.
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Systems biology.
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Drug Discovery-- methods.
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Systems Biology.
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Drug development.
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Systems biology.
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| Dewey Classification
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615/.19
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| LC Classification
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RM301.25.S97 2010
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| NLM classification
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QV744S995 2010
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| Added Entry
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Yan, Qing,1971-
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