Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy ...

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" Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy System Using GEANT4 "
String, Shawn Muhammad, Wazir

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	1054093
Doc. No	:	TL53210
Main Entry	:	String, Shawn
Title & Author	:	Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy System Using GEANT4\ String, ShawnMuhammad, Wazir
College	:	Florida Atlantic University
Date	:	2020
Degree	:	M.S.
student score	:	2020
Note	:	58 p.
Abstract	:	Proton therapy with pencil beam scanning technique is a novel technique to treat cancer patients due to its unique biophysical properties. However, a small error in dose calculation may lead towards undesired greater uncertainties in planed doses. This project aims to create a simulation model of Varian ProBeam Compact using the GEANT4 Monte Carlo simulation tool kit. Experimental data from the first clinical ProBeam Compact system at South Florida Proton Therapy Institute was used to validate the simulation model. A comparison was made between the experimental and simulated Integrated Depth-Dose curves using a 2%/2mm gamma index test with 100% of points passing. The beam spot standard deviation sizes (_S) were compared using percent deviation. All simulated _S matched the experimental _S within 2.5%, except 70 and 80 MeV. The model can be used to develop a more comprehensive model as an independent dose verification tool and further investigate dose distribution.
Descriptor	:	Cancer therapies
	:	Monte Carlo simulation
	:	Physics
	:	Protons
Added Entry	:	Muhammad, Wazir
Added Entry	:	Florida Atlantic University