Spathodea Campanulata:

مرکز و کتابخانه مطالعات اسلامی به زبان های اروپایی

منو

" Spathodea Campanulata: "
Gert Laekeman

Document Type	:	AL
Record Number	:	1064316
Doc. No	:	LA107945
Call No	:	‭10.1163/2031356X-00802004‬
Language of Document	:	English
Main Entry	:	Gert Laekeman
Title & Author	:	Spathodea Campanulata: [Article] : Een Antidiabetisch Geneesmiddel?\ Gert Laekeman
Publication Statement	:	Leiden: Brill
Title of Periodical	:	Afrika Focus
Date	:	1992
Volume/ Issue Number	:	8/2
Page No	:	131–144
Abstract	:	Decoctions of the stem back of Spathodea campanulata (SC) are currently used in Rwanda to treat insulin- and non insulin-dependent diabetics. In order to confirm and farther examine hypoglycemic activity of this plant we set up a research project with as final objective a possible standardisation of Spathodea in antidiabetic therapy in Rwanda. Up to now we were able to confirm the blood sugar lowering effect of SC in hyperglycemic mice (hyperglycemia provoked by streptozotocin = SZ). Also hyperglycemia in glucose loaded mice (glucose tolerance test = GTT) could be tempered by SC. Despite these clearcut hypoglycemic activity, no rise of insulin was seen in the SC treated mice. The activity must be due to some other mechanism of action. The search for active principles did not lead to satisfying results up to now. We have only indirect evidence for the presence of sugar-like compounds, as SC decoctions enhance the glycemia transiently. Some hypotheses are formulated with regard to mechanisms of action and active compounds of SC. These aspects will guide future research. Decoctions of the stem back of Spathodea campanulata (SC) are currently used in Rwanda to treat insulin- and non insulin-dependent diabetics. In order to confirm and farther examine hypoglycemic activity of this plant we set up a research project with as final objective a possible standardisation of Spathodea in antidiabetic therapy in Rwanda. Up to now we were able to confirm the blood sugar lowering effect of SC in hyperglycemic mice (hyperglycemia provoked by streptozotocin = SZ). Also hyperglycemia in glucose loaded mice (glucose tolerance test = GTT) could be tempered by SC. Despite these clearcut hypoglycemic activity, no rise of insulin was seen in the SC treated mice. The activity must be due to some other mechanism of action. The search for active principles did not lead to satisfying results up to now. We have only indirect evidence for the presence of sugar-like compounds, as SC decoctions enhance the glycemia transiently. Some hypotheses are formulated with regard to mechanisms of action and active compounds of SC. These aspects will guide future research.
Descriptor	:	diabetes
Descriptor	:	hypoglycemic activity
Descriptor	:	Rwanda
Descriptor	:	Spathodea campanulata
Location & Call number	:	‭10.1163/2031356X-00802004‬