Association of Obesity Phenotypes with Electrocardiographic Markers of Poor Outcomes in the General ...

مرکز و کتابخانه مطالعات اسلامی به زبان های اروپایی

منو

" Association of Obesity Phenotypes with Electrocardiographic Markers of Poor Outcomes in the General Population "
Ahmad, Muhammad Imtiaz Soliman, Elsayed Z.

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	1104611
Doc. No	:	TLpq2240067218
Main Entry	:	Ahmad, Muhammad Imtiaz
	:	Soliman, Elsayed Z.
Title & Author	:	Association of Obesity Phenotypes with Electrocardiographic Markers of Poor Outcomes in the General Population\ Ahmad, Muhammad ImtiazSoliman, Elsayed Z.
College	:	Wake Forest University
Date	:	2019
student score	:	2019
Degree	:	M.S.
Page No	:	84
Abstract	:	In this thesis, we will evaluate the association of metabolically healthy obesity (MHO) and other obesity phenotypes with common electrocardiographic (ECG) markers such as PR interval, P wave duration, QRS duration, and QT interval. In prior studies, MHO has shown inconsistent association with cardiovascular disease (CVD) and mortality compared to metabolically healthy non-obese (MHNO). However, accumulating evidence suggestive of the heightened risk of CVD and mortality with MHO has raised concerns about the existence of truly benign obesity. An examination of the association of obesity phenotypes with ECG markers can give insight into the pathophysiological basis of poor outcomes associated with these phenotypes. We hypothesized that MHO and other obesity phenotypes would be associated with prevalent ECG markers. We performed a cross-sectional analysis of the association of obesity phenotypes with ECG markers in participants from the Third National Health and Nutrition Examination Survey (NHANES-III). The first chapter of this thesis will be a literature review and will discuss the definition, characteristics of MHO and possible reasons for the controversial association of MHO with CVD. We will also discuss possible pathways through which obesity and MetS are associated with ECG abnormalities. The second chapter will be the manuscript of the association of obesity phenotypes with ECG markers. The third chapter is comprised of examination of association of anthropometric measures of abdominal adiposity and overall obesity with ECG markers.
Subject	:	Epidemiology
	:	Medicine