Development of X-Ray Methods for the Investigation of Protein Dynamics

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" Development of X-Ray Methods for the Investigation of Protein Dynamics "
Wolff, Alexander Michael Fraser, James S.

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	1113747
Doc. No	:	TLpq2385696040
Main Entry	:	Fraser, James S.
	:	Wolff, Alexander Michael
Title & Author	:	Development of X-Ray Methods for the Investigation of Protein Dynamics\ Wolff, Alexander MichaelFraser, James S.
College	:	University of California, San Francisco
Date	:	2020
student score	:	2020
Degree	:	Ph.D.
Page No	:	167
Abstract	:	Throughout history, methodological innovations have resulted in breakthroughs in our understanding of biology. Methods for determining static protein structures, as well as those for probing protein dynamics, are well-established. Nonetheless, visualizing molecules as dynamic entities that respond to their environment is still an outstanding challenge. Specifically, it is challenging to measure the spatial position of all the atoms within a molecule as a function of time. That challenge is the broad focus of this dissertation.
Subject	:	Biophysics
	:	Diffuse scattering
	:	Protein dynamics
	:	Structural biology
	:	Temperature jump
	:	X-ray diffraction