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" Acute myeloid leukemia : "
edited by Paolo Fortina (Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, PA, USA), Eric Londin (Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA), Jason Y. Park (Department of Pathology, UT Southwestern Medical Center and Children's Medical Center, Dallas, TX, US), Larry J. Kricka (Department of Pathology, and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA).
Document Type
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BL
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Record Number
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492843
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Doc. No
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b330356
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Title & Author
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Acute myeloid leukemia : : methods and protocols /\ edited by Paolo Fortina (Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, PA, USA), Eric Londin (Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA), Jason Y. Park (Department of Pathology, UT Southwestern Medical Center and Children's Medical Center, Dallas, TX, US), Larry J. Kricka (Department of Pathology, and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA).
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Publication Statement
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New York, NY :: Humana Press,, [2017]
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Series Statement
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Methods in molecular biology,; 1633
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Springer protocols
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Page. NO
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xi, 278 pages :: illustrations ;; 27 cm.
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ISBN
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9781493971404
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: 1493971409
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9781493971428 (eBook)
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Abstract
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This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.
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Subject
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Acute myeloid leukemia, Laboratory manuals.
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Subject
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Leukemia, Myeloid, Acute-- diagnosis.
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Subject
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Leukemia, Myeloid, Acute-- genetics.
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Subject
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Molecular Diagnostic Techniques.
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Subject
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Prognosis.
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Subject
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Acute myeloid leukemia.
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LC Classification
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RC643.A3264 2017
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NLM classification
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W1ME9616J v.1633 2017
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WH 25
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Added Entry
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Fortina, Paolo
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Londin, Eric
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Park, Jason Y.
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Kricka, Larry J.,1947-
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