Molecular markers and human history: A tale of two haplogroup systems

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منو

" Molecular markers and human history: A tale of two haplogroup systems "
Diane J. Rowold R. J. Herrera

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	54240
Doc. No	:	TL24194
Call number	:	‭3217579‬
Main Entry	:	Diane J. Rowold
Title & Author	:	Molecular markers and human history: A tale of two haplogroup systems\ Diane J. Rowold
College	:	Florida International University
Date	:	2006
Degree	:	Ph.D.
student score	:	2006
Page No	:	198
Abstract	:	To chronicle demographic movement across African Asian corridors, a variety of molecular (sequence analysis, restriction mapping and denaturing high performance liquid chromatography etc.) and statistical (correspondence analysis, AMOVA, calculation of diversity indices and phylogenetic inference, etc.) techniques were employed to assess the phylogeographic patterns of mtDNA control region and Y chromosomal variation among 14 sub-Saharan, North African and Middle Eastern populations. The patterns of genetic diversity revealed evidence of multiple migrations across several African Asian passageways as well within the African continent itself. The two-part analysis uncovered several interesting results which include the following: (1) a north (Egypt and Middle East Asia) to south (sub-Saharan Africa) partitioning of both mtDNA and Y chromosomal haplogroup diversity, (2) a genetic diversity gradient in sub-Saharan Africa from east to west, (3) evidence in favor of the Levantine Corridor over the Horn of Africa as the major genetic conduit since the Last Glacial Maximum, (4) a substantially higher mtDNA versus Y chromosomal sub-Saharan component in the Middle East collections, (5) a higher representation of East versus West African mtDNA haplotypes in the Arabian Peninsula populations versus no such bias in the Levant groups and lastly, (6) genetic remnants of the Bantu demographic expansion in sub-Saharan Africa.
Subject	:	Biological sciences; Haplogroup; Human history; Molecular markers; mtDNA; Genetics; 0369:Genetics
Added Entry	:	R. J. Herrera
Added Entry	:	Florida International University