Derivatives of benzotiazoles and oxiranos as antifungal agents

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" Derivatives of benzotiazoles and oxiranos as antifungal agents "
Dioselina Torres Carrasquillo S. C. Cantrell, Osvaldo

Document Type	:	Latin Dissertation
Language of Document	:	Spanish
Record Number	:	55221
Doc. No	:	TL25175
Call number	:	‭1451039‬
Main Entry	:	Dioselina Torres Carrasquillo
Title & Author	:	Derivatives of benzotiazoles and oxiranos as antifungal agents\ Dioselina Torres Carrasquillo
College	:	Universidad del Turabo (Puerto Rico)
Date	:	2006
Degree	:	M.S.
student score	:	2006
Page No	:	32
Abstract	:	A study was conducted with five Chemical compounds: 2-cianomehyl-1,3-benzothiazol (CNBT), 2-metil-1,3-benzotiazol (MBT), 2-amino-4-(benzotiazol-2-il)-5-(2-cloro-5-nitrofenil)tiazol (tiazol), 2-(1,3-benzotiazol-2-il)-3-(2-cloro-5-nitrofenil)oxirano-2-carbonitrilo (epoxide), 3-(2,4-diclorofenil)-2-(fenil)oxirano-2-carbonotrilo (fenil) (benzotiazoles and oxiranos). In order to test the degree of inhibition of these Chemical compounds on the following species, Aspergillus niger, Aspergillus versicolor and Penicillium funiculosum, the compundsa were dissolved in 70% ethanol. Each compound was prepared in a base solution of 1 mg/mL concentration. From this solution three concentrations were prepared (0.1 mg/mL, 0.01 mg/mL, and 0.001 mg/mL). Using the PDA culture method (Potato Dextrose Agar), the species were inoculated in three concentrations. Radial growth of the three species was measured during 5 days. These chemical compounds completely inhibited the growth of these species at the concentration of 0.1 mg/mL. The compounds fenil, tiazol and epóxido provided excellent inhibition during the first 48 hours at concentrations of 0.01 mg/mL and 0.001 mg/mL. At the lower concentration the chemical compound that provided the best inhibition was fenil.
Subject	:	Health and environmental sciences; Environmental science; 0768:Environmental science
Added Entry	:	S. C. Cantrell, Osvaldo
Added Entry	:	Universidad del Turabo (Puerto Rico)