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" Current Topics in Cellular Regulation : "
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BL
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554409
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b382939
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Bernard L Horecker
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Current Topics in Cellular Regulation : : Volume 31.
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| Publication Statement
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Saint Louis : Elsevier Science,, 2015.
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Current topics in cellular regulation.
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(289 pages).
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1483217302
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: 9781483217307
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II. The Beginning: How It All Started.
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| Contents
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Front Cover Current Topics in Cellular Regulation Copyright Page Table of Contents Chapter 1. Calcium as Intracellular Messenger: From Simplicity to Complexity I. Introduction II. The Simplicity of Ca2+ as Messenger III. Ca2+ and Cyclic AMP as Synarchic Messengers IV. Ca2+ Metabolism and Calcium Homeostasis during Sustained Cellular Responses V. Ca2+ as Messenger in Sustained Cellular Responses VI. Time-Dependent Changes in Cell Responsiveness VII. The Complexity and Elegance of Ca2+ Messenger Generation, Readout, and Action REFERENCES. Chapter 2. The Integration of Receptor-Regulated Intracellular Calcium Release and Calcium Entry across the Plasma MembraneI. Introduction II. Sources of Activator Calcium III. Mechanisms of Intracellular Calcium Release IV. Mechanisms of Calcium Entry V. Conclusions REFERENCES Chapter 3. The Role of Calcium in Neurotransmitter Release: Existing Models and New Approaches to Evaluate Possible Mechanisms I. Introduction II. Current Models of the Mechanism of Synaptic Release III. Experimental Models and Techniques Applied to the Study of Secretion. IV. Role of Second Messengers in ExocytosisV. Concluding Remarks REFERENCES Chapter 4. Regulation of Free Calmodulin Levels in Neurons by Neuromodulin: Relationship to Neuronal Growth and Regeneration I. Discovery of Neuromodulin as a Calmodulin-Binding Protein II. Distribution of Neuromodulin within Brain III. Physical Properties of Neuromodulin IV. Primary Amino Acid Sequence of Neuromodulin and Identification of Its Calmodulin-Binding Domain V. Regulation of Calmodulin Binding to Neuromodulin by Protein Kinase C Phosphorylation and Calcineurin Dephosphorylation. VI. Cloning of cDNAs Encoding Neuromodulin and Expression of the Protein in Escherichia coliVII. Recognition of the Homology between Neuromodulin and GAP-43 Physiological Functions of the Protein VIII. Biochemical Model for Regulation of Neurite Extension by Neuromodulin REFERENCES Chapter 5. Calcium/Calmodulin-Dependent Protein Kinase II I. Introduction II. The CaM Kinase II Isozyme Family III. Substrate Consensus Phosphorylation Sequence IV. Regulatory Properties of CaM Kinase II V. Identification of Regulatory Domains of CaM Kinase II VI. Physiological Role of CaM Kinase II. VII. SummaryREFERENCES Chapter 6. The Molecular Structure and Regulation of Muscular Calcium Channels I. Introduction II. Composition of the Skeletal Muscle CaCB Receptor/ Calcium Channel III. Primary Sequence of the Channel Subunits IV. Binding Characteristics of the Purified Channel V. Reconstitution of the Calcium Channel Receptor Complex and Its Physiological Function VI. Structure of Nonskeletal Muscle L-Type Calcium Channels VII. In Vivo Regulation and Conclusion REFERENCES Chapter 7. Na+-Ca2+ Exchanger: The Elusive Protein I. Introduction.
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| Abstract
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Current Topics in Cellular Regulation: Volume 31 is a collection of papers that deals with the role of calcium as intracellular messenger, calcium release or entry across the plasma membrane, calcium in neurotransmitter release, and the regulation of free calmodulin levels in neurons by neuromodulin. Other papers discuss the calcium/calmodulin-dependent protein kinase II, the regulation of muscular calcium channels,Current Topics in Cellular Regulation: Volume 31 is a collection of papers that deals with the role of calcium as intracellular messenger, calcium release or entry across the plasma membrane, calcium in neurotransmitter release, and the regulation of free calmodulin levels in neurons by neuromodulin. Other papers discuss the calcium/calmodulin-dependent protein kinase II, the regulation of muscular calcium channels,Current Topics in Cellular Regulation: Volume 31 is a collection of papers that deals with the role of calcium as intracellular messenger, calcium release or entry across the plasma membrane, calcium in neurotransmitter release, and the regulation of free calmodulin levels in neurons by neuromodulin. Other papers discuss the calcium/calmodulin-dependent protein kinase II, the regulation of muscular calcium channels,",,,,,"Current Topics in Cellular Regulation: Volume 31 is a collection of papers that deals with the role of calcium as intracellular messenger, calcium release or entry across the plasma membrane, calcium in neurotransmitter release, and the regulation of free calmodulin levels in neurons by neuromodulin. Other papers discuss the calcium/calmodulin-dependent protein kinase II, the regulation of muscular calcium channels, and the Na+-Ca2+ exchangers. One paper describes the mechanisms of intracellular calcium release or entry in which agonists acting through the phosphoinositide system, or possibly.
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Electronic books
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Earl R Stadtman
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P Boon Chock
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