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" Nucleic acid crystallography "
edited by Eric Ennifar, CNRS "Architecture et Réactivité de IʼARN", Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
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BL
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| Record Number
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569104
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| Doc. No
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b398323
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| Title & Author
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Nucleic acid crystallography : methods and protocols /\ edited by Eric Ennifar, CNRS "Architecture et Réactivité de IʼARN", Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
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| Publication Statement
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New York :: Humana Press,, [2016]
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| Series Statement
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Methods in molecular biology,; 1320
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Springer protocols
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| ISBN
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9781493927623
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9781493927630
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Includes bibliographical references and index.
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| Abstract
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"This volume includes comprehensive and up-to-date coverage of all nucleic-acid-specific steps used in X-ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the book. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Nucleic Acid Crystallography: Methods and Protocols presents protocols that are aimed at both researchers and students who are interested in the structural biology of DNA or RNA, alone or in complex with proteins or ligands"--
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| Subject
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Nucleic acids, Laboratory manuals.
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Crystallography, Laboratory manuals.
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| Subject
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Nucleic Acids-- ultrastructure.
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Crystallography, X-Ray-- methods.
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Molecular Structure.
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| Added Entry
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Ennifar, Eric.
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Springer Science+Business Media.
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