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" Whole genome amplification "
edited by Thomas Kroneis, Institute of Cell Biology, Histology & Embryology, Medical University of Graz, Graz, Austria.
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BL
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| Record Number
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569130
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| Doc. No
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b398349
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| Title & Author
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Whole genome amplification : methods and protocols /\ edited by Thomas Kroneis, Institute of Cell Biology, Histology Embryology, Medical University of Graz, Graz, Austria.
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| Publication Statement
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New York :: Humana Press,, [2015]
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| Series Statement
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Springer protocols,
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Methods in molecular biology,; v. 1347
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| ISBN
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9781493929894
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: 1493929895
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9781493929900
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Abstract
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This volume mirrors the holistic feature of whole genome amplification (WGA) technology by combining reviews, detailed basic methods and advanced sample workflows. The first part of the book covers an overview of the development of WGA techniques throughout recent years including general considerations on bias in WGA, possible sample pre-enrichment strategies and how to run a single-cell lab. The second part focuses on major WGA methods and protocols that allow the assessment of WGA product quality. The final chapters contain advanced protocols and address issues such as sample preparation using laser-micro dissection; WGA from partially degraded DNA (formalin-fixed paraffin embedded samples); circulating tumor cells; and ancient samples.--
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| Subject
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Gene amplification, Laboratory manuals.
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Genomics, Laboratory manuals.
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| Subject
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Gene Amplification.
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Genomics.
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| Added Entry
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Kroneis, Thomas.
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