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" PTEN "
edited by Leonardo Salmena, Department of Pharmacology and Toxicology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON, Canada, Vuk Stambolic, University of Toronto, Princess, MArgaret Cancer Centre, Toronto, ON, Canada.
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BL
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| Record Number
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569166
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b398385
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| Title & Author
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PTEN : methods and protocols /\ edited by Leonardo Salmena, Department of Pharmacology and Toxicology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON, Canada, Vuk Stambolic, University of Toronto, Princess, MArgaret Cancer Centre, Toronto, ON, Canada.
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| Publication Statement
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New York :: Humana,, [2016]
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| Series Statement
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Methods in molecular biology,; 1388
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Springer protocols
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| ISBN
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9781493932979
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: 1493932977
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: 9781493932993
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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PTEN: history of a tumor suppressor / Leonardo Salmena -- PTEN at 18 : still growing / Olena Gorbenko and Vuk Stambolic -- Immunopathologic assessment of PTEN expression / Mireia Castillo-Martin, Tin Htwe Thin, Ana Collazo Lorduy, and Carlos Cordon-Cardo -- Measurement of PTEN by flow cytometry / Jolm F. Woolley and Leonardo Salmena -- Detecting PTEN and PI3K signaling in brain / Guo Zhu and Suzanne J. Baker -- Germline PTEN mutation analysis for PTEN hamartoma tumor syndrome / Joanne Ngeow and Charis Eng -- Methods for assessing the in vivo role of PTEN in glucose homeostasis / Cynthia T. Luk, Stephanie A. Schroer, and Minna Woo -- Rapid detection of dynamic PTEN regulation in living cells using intramolecular BRET / Stanislas Misticone, Evelyne Lima-Fernandes, and Mark G.H. Scott -- Methods for the identification of PTEN-targeting MicroRNAs / Andrea Tuccoli, Marianna Vitiello, Andrea Marranci, Francesco Russo, and Laura Poliseno -- Posttranscriptional regulation of PTEN by competing endogenous RNAs / Yvonne Tay and Pier Paolo Pandolfi -- In cell and in vitro assays to measure PTEN ubiquitination / Amit Gupta, Helene Maccario, Nisha Kriplani, and Nicholas R. Leslie -- Assessing PTEN subcellular localization / Anabel Gil, José I. López, and Rafael Pulido -- Methods to study PTEN in mitochondria and endoplasmic reticulum / Sonia Missiroli, Claudia Morganti, Carlotta Giorgi, and Paolo Pinton -- Methods in the study of PTEN structure : X-ray crystallography and hydrogen deuterium exchange mass spectrometry / Glenn R. Masson, John E. Burke, and Roger L. Williams -- Methods for PTEN in stem cells and cancer stem cells / Suzanne Schubbert, Jing Jiao, Marcus Ruscetti, Jonathan Nakashima, Shumin Wu, Hong Lei, Qinzhi Xu, Wenkai Yi, Haichuan Zhu, and Hong Wu -- Modeling cancer-associated mutations of PTEN in mice / Antonella Papa and Pier Paolo Pandolfi -- C. elegans methods to study PTEN / Shanqing Zheng and Ian D. Chin-Sang.
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| Abstract
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This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology.
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Phosphatases.
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Cellular signal transduction.
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PTEN Phosphohydrolase
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Tumor Suppressor Proteins
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| Added Entry
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Salmena, Leonardo.
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Stambolic, Vuk.
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