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" In silico systems biology "
edited by Maria Victoria Schneider.
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BL
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| Record Number
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569613
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b398832
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| Title & Author
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In silico systems biology\ edited by Maria Victoria Schneider.
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| Publication Statement
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New York :: Humana Press ;: Springer,, c2013.
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| Series Statement
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Methods in molecular biology ;; 1021
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Springer protocols
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| ISBN
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9781627034494
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: 1627034498
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: 9781627034500
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: 1627034501
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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1. Defining systems biology : a brief overview of the term and field / Maria Victoria Schneider -- 2. Approaches to modeling gene regulatory networks : a gentle introduction / Thomas Schlitt -- 3. Integration of genomic information with biological networks using cytoscape / Anna Bauer-Mehren -- 4. Visualization and analysis of biological networks / Pablo Porras Millán -- 5. Modeling signaling networks with different formalisms : a preview / Aidan MacNamara, David Henriques, and Julio Saez-Rodriguez -- 6. From a biological hypothesis to the construction of a mathematical model / David Cohen, Inna Kuperstein, Emmanuel Barillot, Andrei Zinopyev and Laurence Calzone -- 7. Practical use of BiNoM : a biological network manager software / Eric Bonnet, Laurence Calzone, Daniel Rovera, Gautier Stoll, Emmanuel Barillot and Andrei Zinovyev -- 8. Using chemical kinetics to model biochemical pathways / Nicolas Le Novère and Lukas Endler -- 9. Simulation of stochastic kinetic models / Andrew Golightly and Colin S. Gillespie -- 10. BioModels database : a repository of mathematical models of biological processes / Vijayalakshmi Chelliah, Camille Laibe and Nicolas Le Novère -- 11. Supporting SBML as a model exchange format in software applications / Sarah M. Keating and Nicolas Le Novère -- 12. Controlled annotations for systems biology / Nick Juty, Camille Laibe, and Nicolas Le Novère -- 13. Bayesian approaches for mechanistic ion channel modeling / Ben Calderhead, Michael Espstein, Lucia Sivilotti and Mark Girolami -- 14. Building models using reactome pathways as templates / David Croft -- 15. Uniform curation protocol of metazoan signaling pathways to predict novel signaling components / Máté Pálfy, Illés J. Farkas, Tibor Vellai and Tamás Korcsmáros -- 16. Bioinformatics workflows and web services in systems biology made easy for experimentalists / Rafael C. Jimenez and Manuel Corpas.
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| Abstract
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Systems biology can now be considered an established and fundamental field in life sciences. It has moved from the identification of molecular 'parts lists' for living organisms towards synthesising information from different 'omics'-based approaches to generate and test new hypotheses about how biological systems work. In Silico Systems Biology: Methods and Protocols, expert researchers in the field detail a practical set of chapters based often on actual materials used and develop for face-to-face training with examples and case studies.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step workflows, and key tips on troubleshooting and avoiding known pitfalls. --
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Systems biology, Laboratory manuals.
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Systems Biology-- methods.
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| Subject
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Computer Simulation.
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| Subject
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Models, Theoretical.
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| Added Entry
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Schneider, Maria Victoria.
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