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" Transgenic mouse methods and protocols "
edited by Marten H. Hofker, Jan M. van Deursen.
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BL
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| Record Number
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576081
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b405300
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| Title & Author
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Transgenic mouse methods and protocols\ edited by Marten H. Hofker, Jan M. van Deursen.
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| Edition Statement
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2nd ed.
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| Publication Statement
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New York :: Humana Press,, c2011.
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| Series Statement
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Springer protocols
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Methods in molecular biology,; 693
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| ISBN
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9781607619734
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: 1607619733
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: 9781607619741
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: 1607619741
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| Notes
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Previous ed.: 2003.
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Introduction: strategies for developing genetically modified mice / Marten H. Hofker -- Genetic modification of the mouse : general technology-pronuclear and blastocyst injection / Jan Willem Voncken -- Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos / Jérôme Artus and Anna-Katerina Hadjantonakis -- Cryopreservation of mouse spermatozoa and in vitro fertilization / Naomi Nakagata -- Autopsy and histological analysis of the transgenic mouse / Marion J.J. Gijbels and Menno P.J. de Winther -- Transgene design / Bart van de Sluis and Jan Willem Voncken -- Inducible transgenic mouse models / Thomas L. Saunders -- Lentiviral transgenesis / Terunaga Nakagawa and Casper C. Hoogenraad -- Transgenesis in mouse embryonic stem cells / Janine van Ree, Wei Zhou, Ming Li, and Jan M. van Deursen -- Engineering BAC reporter gene constructs for mouse transgenesis / Yu Fu and Peter Maye -- Targeting vector construction through recombineering / Liviu A. Malureanu -- Generating conditional knockout mice / Roland H. Friedel, Wolfgang Wurst, Benedikt Wefers, and Ralf Kühm -- Hypomorphic mice / Darren J. Baker -- MICER targeting vectors for manipulating the mouse genome / Chunhong Liu, Paul F. Szurek, and Y. Eugene Yu -- Knock-in approaches / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Generation of a series of knock-in alleles using RMCE in ES cells / Anton J.M. Roebroek, Philip L.S.M. Gordts, and Sara Reekmans -- Selection of targeted mutants from a library of randomly mutagenized ES cells / Kyoji Horie, George Gaitanaris, and Alexander Gragerov -- Generation of genetically modified rodents using random ENU mutagenesis / Ruben van Boxtel and Edwin Cuppen -- Bone marrow transplantations to study gene function in hematopoietic cells / Menno P.J. de Winther and Peter Heeringa -- Adenovirus-mediated gene transfer / Ko Willems van Dijk, Kyriakos E. Kypreos, Frits J. Fallaux, and Jurre Hageman.
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Transgenic mice, Laboratory manuals.
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| Added Entry
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Hofker, Marten H., (Marten Harro)
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Deursen, Jan van,1930-
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