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" Nisoldipine 1987 "
edited by P. G. Hugenholtz, J. Meyer.
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BL
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| Record Number
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577477
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b406696
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| Main Entry
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Hugenholtz, P. G.
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| Title & Author
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Nisoldipine 1987\ edited by P. G. Hugenholtz, J. Meyer.
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| Publication Statement
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Berlin, Heidelberg :: Springer Berlin Heidelberg,, 1987.
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| ISBN
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9783642730108
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: 9783540183945
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| Contents
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Experimental and Clinical Pharmacology -- Experimental Pharmacology of Nisoldipine: Perspectives from Long-Term-Studies -- Membrane Potential and Nisoldipine Block of Calcium Channels in the Heart: Interactions with Channel Gating -- Review of Nisoldipine Binding Studies -- Comparison of Nifedipine and Nisoldipine on Human Arteries and Human Cardiac Tissues In Vitro -- Effect of Prolonged Treatment with Nisoldipine on Cholesterol Deposition and Cardiac Noradrenaline Reserves: A Comparative Study -- Pharmacokinetics of Nisoldipine -- Plasma Level-Effect Relationships for some Acute Cardiovascular Effects of Nisoldipine and Other Dihydropyridine Calcium Channel Antagonists -- Pharmacokinetics and Haemodynamic Effects ofNisoldipine in Patients with Liver Cirrhosis -- Steady-State Pharmacokinetics of Nisoldipine in Patients with Liver Disease -- Biotransformation of Nisoldipine in Man -- Effect of Nisoldipine on Electrophysiological Parameters in Man -- Chairman's Analysis -- Effects on Coronary Arteries: Role of Vasomotor Tone -- Effect of Nisoldipine on Variant Angina -- Hemodynamic Effects of Intravenous Nisoldipine -- Direct Cardiac and Peripheral Vascular Effects of lntracoronary Nisoldipine -- Antianginal Efficacy of Nisoldipine in Patients with Unstable Angina Pectoris: Evaluation on Holter ECG -- Attenuation by Nisoldipine of the Abnormal Response to Cold Pressor Stimulation in Patients with Ischaemia and Normal Coronary Arteries -- Nisoldipine for Patients Undergoing Coronary Revascularisation -- Cardiovascular Profile of Nisoldipine as Compared to Nifedipine in Dogs 131 -- The Effect of Nisoldipine on Experimentally Induced Renal Failure -- Nisoldipine Delays Progression of Chronic Renal Failure in Man Irrespective of Change in Blood Pressure -- Influence of Nisoldipine on Hemodynamics and Atrial Natriuretic Polypeptides at Exercise Loading in Hypertensive Patients -- Coronary Vasomotility with Different Intravenous Doses of Nisoldipine -- Hemodynamic Effects of Intravenous Nisoldipine and Nitroglycerin in Patients with Coronary Heart Disease -- Effects on Ventricular Function -- Acute Hemodynamic Effects of Intravenous Nisoldipine in Patients with Left Ventricular Failure -- Hemodynamic Effects of Long-Term Oral Nisoldipine Versus Placebo in Patients with Impaired Ventricular Function -- A Comparison of the Acute Hemodynamic Effects of Nifedipine and Nisoldipine in Patients with Ischemic Reduced Left Ventricular Function -- Nisoldipine After Acute Myocardial Infarction: Comparison with Other Calcium Channel Blocking Agents -- Assessment of Long-Term Efficacy and Tolerability of Nisoldipine by the Clinical Data Pool -- Chairman's Analysis -- Effects in Stable Angina and Ischemia -- Effects of Long-Term Therapy with the Association of Nisoldipine and a Beta-Blocker on Exercise Tolerance and Coronary Hemodynamics in Patients with Stable Angina: A Comparison with Monotherapy -- Is There a Difference between the Acute and Chronic Anti-Ischemic Efficacy of Nisoldipine? -- Nisoldipine Versus Mononitrate in Stable Angina -- Efficacy ofNisoldipine Compared with Nifedipine in Chronic Stable Angina Pectoris -- Effect of Nisoldipine and Nitroglycerin on Myocardial Ischemia and Dysfunction During Coronary Angioplasty -- Anti-Ischemic Effect of Nisoldipine in Patients with Stable Angina Pectoris -- Efficacy of Nisoldipine in Chronic Stable Angina in Patients Taking Beta-Blockers -- Assessment and Comparison of Single and Double Dose of Nisoldipine in the Prevention of Exercise-Induced Ischaemia - Match with Sublingual Nitroglycerin -- Acute Hemodynamic Response ot Intravenous Nisoldipine (Bay k 5552) = Versus Nifedipine in Patients with Ischemic Cardiomyopathy -- Chairman's Analysis -- Silent Ischemia -- The Relevance of Silent Ischemia for the Clinician -- Prognostic Significance of Ischemic Changes in Patients After Myocardial Infarction -- Effect ofNisoldipine on Myocardial Ischeinia: Evaluation by Holter Monitoring -- Calcium Antagonists in Silent Myocardial Ischeinia-Preliminary Results with Nisoldipine -- Effects of Oral Nisoldipine on Transient and Exercise-Induced Ischaeinia in Patients with Coronary Heart Disease -- Improvement in Silent Myocardial Ischemia with Nisoldipine -- Heart Failure -- Vasodilators in the Treatment of Chronic Heart Failure - An Overview -- Hemodynamic Effects of Nisoldipine in Patients with Severe Heart Failure -- Acute Effects of Intravenous Nisoldipine on Hemodynamics and Left Ventricular Function in Cardiac Failure -- Effects of Nisoldipine in Heart Failure -- Hemodynamic Effects of Nisoldipine in Patients with Severe Chronic Congestive Heart Failure -- Influence of Chronic Nisoldipine Therapy upon Severe Congestive Heart Failure - Comparison with Nitrates -- Chairman's Analysis -- Closing Remarks.
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| Abstract
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This book, the first to provide a comprehensive overview of all studies so far carried out with this second-generation calcium entry blocker, Nisoldipine, is the fruit of a- day conference. In the first part the essential data on its experimental and clinical pharmacology are summarised by outstanding research workers in this field. The second part contains work concerning the major action of the drug, namely its effect in reducing vasomotor tone. The third part deals with intravenous or oral administration. From these data a clear profile develops, which is effective in angina pectoris of various forms and in cardiac ischaemia, both the clinically evident and the silent forms. Additionally, exploratory data in the area of cardiac failure are presented. As several contributors are based on material presented as a poster they do not contain a reference list. This book is highly recommended for all those investigators and clinicians who are researching for the optimal calcium entry blocker.
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| Subject
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Medicine.
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Toxicology.
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Cardiology.
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| Added Entry
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Meyer, J.
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SpringerLink (Online service)
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