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" Selenium in Biology and Medicine "
edited by Albrecht Wendel.
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BL
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578335
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b407554
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Selenium in Biology and Medicine\ edited by Albrecht Wendel.
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XVII, 330 p. :: online resource.
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9783642744211
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| Contents
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I Biochemistry of Selenoproteins and Selenium Compounds -- The Regulation of Glutathione Peroxidase Gene Expression; Implication for Species Difference and the Effect of Dietary Selenium Manipulation -- Regulation of Expression of Glutathione Peroxidase by Selenium -- Studies on New Selenoproteins and Specific Selenium Target Tissues -- Selenium-Containing Proteins in Plasma of Higher Primates -- Involvement of a Selenoprotein in Glycine, Sarcosine, and Betaine Reduction by Eubacterium acidaminophilum -- Dependence of Mouse Liver Phospholipid Hydroperoxide Glutathione Peroxidase on Dietary Selenium -- Interaction of Heparin with a Selenoprotein in Human Plasma -- Selenium-Independent Glutathione Peroxidase in Malaria Parasites -- Synthesis of a Selenium Analogue of Neurospora crassa Metallothionein and Its Properties -- Reactions of the Thioredoxin System with Selenium -- Selenite-Induced Variation of Glutathione Peroxidase Activity in Mammalian Cells and Its Consequences for Cellular Radiation Resistance -- Effects of Selenium Supplementation on Platelet Function as Assessed by Platelet Aggregation and Glutathione Peroxidase Activity -- Role of Glutathione Peroxidase and ?-Tocopherol in Protecting Rat Erythrocytes Against tert-Butyl Hydroperoxide-Induced Hemolysis in Vitro -- Active Oxygen Generation by the Reaction of Selenite with Reduced Glutathione in Vitro -- Studies on Selenite-Induced DNA Fragmentation and the Role of Poly (ADP-Ribose) Polymerase in Selenite Toxicity -- Involvement of Cellular Sulfhydryl Compounds in the Inhibition of DNA and RNA Synthesis by Selenite -- II Influence of Selenium on the Metabolism of Animals and Man -- Selenium-Dependent Metabolic Modulations in Mouse Liver -- Selenium Deficiency and Thyroid Hormone Metabolism -- Glutathione Metabolism as Affected by Selenium Deficiency -- Selenium Deficiency and the Metabolism of Ketone Bodies -- Transport of Selenomethionine and Methionine Across the Intestinal Brush Border Membrane -- Plasma Malondialdehyde and Exhaled Hydrocarbons: Are They Reliable Indicators of Lipid Peroxidation and Glutathione Peroxidase Activity? -- Biochemical Studies on Selenium and Keshan Disease \U+2014\ The Oxidant Stress and Defence Capacity in Blood of Selenium-Deficient Children -- Effect of Growth Phase on Deposition of Selenium (Se) in Tissues of Rats Fed Elevated Dietary Levels of Se as Either L-Selenomethionine or Sodium Selenate -- Selenium Intake Induces Growth Retardation Through Reversible Growth Hormone and Irreversible Somatomedin C Suppression -- Selenium in the Central Nervous System of the Rat After Exposure to 75-Se-L-Selenomethionine -- Effect of Selenium on Adriamycin-Induced Cardiotoxicity in Mice -- Effects of Selenium Deficiency on Mouse Articular Cartilage -- Myocardial and Pancreatic Damage in Selenium Vitamin E Deficient Mice -- III Biochemical Pharmacology of Selenium Compounds -- Metabolism and Disposition of Ebselen -- The Use of Highly Enriched 77Se in Metabolic Studies of Ebselen in Man \U+2014\ An NMR Investigation -- Effect of Ebselen (PZ-51) in Liver Failure Induced by Propionibacterium acnes (P. Acnes) -- Ebselen (PZ-51) Inhibits the Formation of Ischemic Brain Edema -- Effects of Ebselen (PZ-51) on Experimental Cerebral Vasospasm -- Ebselen, a Seleno-Organic Compound, Inhibits Leukocyte Aggregation and Reduces the Plasma Leukotriene B4 Level in Humans and Rats -- Binding of Ebselen to Plasma Protein -- Protection of Experimental Cobalt Cardiomyopathy in the Rat by Selenium Pretreatment -- Correlation of Levels of Platinum and Selenium in Rats Treated with Cisplatin and Sodium Selenite -- IV Selenium and Human Health -- Progress in Establishing Human Nutritional Requirements and Dietary Recommendations for Selenium -- Supplementation of a Population with Selenium \U+2014\ Reasons for Action and Initial Experience -- Selenium Status and Cardiovascular Disease: Dutch Epidemiologic Data -- Bioavailability of Selenium in a Selected Dutch Population -- Studies of Human Maximal and Minimal Safe Intake and Requirement of Selenium -- Are Germans Selenium-Deficient? -- Blood Selenium Levels of Norwegians Compared to Their Se Intakes -- The Intake of Selenium and Other Nutrients in a Group of Norwegian Rheumatics -- Se Supplementation of Fertilizers Has Increased the Se Intake and Serum-Se Concentration of Finnish People -- Selenium Status of Children and Adults in Northern Germany -- Urinary Excretion of Selenium (Se) and Trimethylselenonium (TMSe) by NZ Women During Long Term Supplementation with Selenate or Selenomethionine (Semet) -- Selenium (Se) and Glutathione Peroxidase (GSH-Px) in Blood Components of NZ Women During Long Term Supplementation with Selenate or Selenomethionine (Semet) -- Comparison of Human Response to Low Doses of Inorganic and Organic Selenium -- The Relativity Between Some Epidemiological Characteristics of Kaschin-Beck Disease and Selenium Deficiency -- The Selenium and Phospholipid (Phosphatidylcholine) Deficiency and Low Temperature of Environment May be the Pathogenetic Basis of Kaschin-Beck Disease -- Low Selenium State and Increased Erucic Acid in Children from Keshan Endemic Areas \U+2014\ A Pilot Study -- Selenium in Children with Acute Leukaemia During Chemotherapy -- Selenium Status and Age Effects -- V Selenium and Malignant Growth -- The Influence of Dietary Selenium on Colon, Pancreas, and Skin Tumorigenesis -- Is Selenium Metabolism Necessary for Its Anticarcinogenic Activity? -- Low Serum Selenium Level and Elevated Risk of Lung Cancer -- Study on the Relation of Se, Mn, Fe and Mo to Liver Cancer Mortality -- Determination of Selenium Contents in Sera, Hair and Glutathione Peroxidase Activities in Whole Blood of Nasopharyngeal Carcinoma (NPC) Patients.
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| Abstract
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In July, 1988, more than 300 scientists from 29 different countries gathered at Tiibingen, W. Germany, in order to spend 4 days discussing their favourite trace element, selenium. This meeting continued the good tradition of three previous meetings held in Corvallis/Oregon, 1976, in Lubbock/Texas, 1980, and in Beijing/China, in 1984. Incidentally, the University of Tiibingen provided a unique historical background for a Symposium devoted to recent advances in biochemistry, pharmacology, human nutrition and human health; here, the first independent depart\U+00ad\ ment of Physiological Chemistry in Germany was founded in 1845. Pro\U+00ad\ fessor H9Ppe-Seyler elucidated here the hemin structure and his student Friedrich Miescher discovered the nucleic acids. This book contains one-half of the oral or poster presentations which were selected before the meeting was held on the basis of a one\U+00ad\ page abstract. It is the reader who will have to decide whether this time\U+00ad\ consuming policy of quality assessment was warranted or not.
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Life sciences.
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Neurosciences.
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Pharmacology.
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Food-- Biotechnology.
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Gastroenterology.
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Hepatology.
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Biochemistry.
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Life sciences.
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Biochemistry, general.
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Pharmacology/Toxicology.
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Neurosciences.
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Food Science.
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Hepatology.
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Gastroenterology.
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Wendel, Albrecht
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SpringerLink (Online service)
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Sponsored by the International Selenium Organizing Committee in cooperation with the Deutsche Forschungsgemeinschaft
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