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" Novel anticancer agents : "
editors, Alex A. Adjei, John K. Buolamwini
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BL
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| Record Number
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580722
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| Doc. No
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GBA552090b409941
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| Title & Author
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Novel anticancer agents : : strategies for discovery and clinical testing /\ editors, Alex A. Adjei, John K. Buolamwini
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| Publication Statement
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Oxford :: Academic Press,, c2006
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| Page. NO
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xv, 437 p., [20] p. of plates :: ill. (some col.) ;; 26 cm
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| ISBN
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0120885611 (hbk.)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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A survey of novel molecular targets for anticancer drug discovery -- Microarrays: small spots produce major advances in pharmacogenomics -- Strategies to target chemotherapeutics to tumors -- QSAR and pharmacophore mapping strategies in novel anticancer drug discovery -- Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery -- Antisense strategies for the development of novel cancer therapeutics -- Antibodies and vaccines as novel cancer therapeutics -- Inhibitors as targets for cancer therapy -- Preclinical testing and validation of novel anticancer agents -- Surrogate end points and biomarkers for early trials of novel anticancer agents -- Regulatory considerations in clinical trials of novel anticancer drugs -- Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics -- Imaging of pharmacodynamic end points in clinical trials -- Devising proof-of-concept strategies in oncology clinical trials -- Clinical trial designs for cytostatic agents and agents directed at novel molecular targets -- Cancer gene therapy clinical trials: from the bench to the clinic -- Molecular targets for radiosensitization -- Patient accrual to clinical trials
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| Subject
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Antineoplastic agents-- Development
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Antineoplastic agents-- Testing
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Antineoplastic Agents
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Clinical Trials as Topic-- methods
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Drug Screening Assays, Antitumor
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Drug Therapy
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Pharmacogenetics
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Research Design
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| Dewey Classification
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616.994061
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| Added Entry
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Adjei, Alex A
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Buolamwini, John K
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