| Document Type
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BL
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| Record Number
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581430
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| Doc. No
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b410649
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| Main Entry
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Migeon, Barbara R
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| Title & Author
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Females are mosaics : : X inactivation and sex differences in disease /\ Barbara R. Migeon
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| Edition Statement
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2nd ed
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| Publication Statement
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Oxford ;New York :: Oxford University Press,, 2014
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| Page. NO
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xviii, 307 p. , [8] p. of plates :: ill. ;; 25 cm
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| ISBN
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9780199927531 (alk. paper)
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: 0199927537 (alk. paper)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Sex differences in disease -- Evolution of the human sex chromosomes and a portrait of the human X -- X chromosome dosage compensation : an overview -- The discovery of X chromosome inactivation -- Experimental models for X inactivation studies -- Theme 1 : the initial step : creating the active and inactive X -- Theme 2 : subsequent steps : spreading and maintaining inactivation -- Variations 1 : evolution of the X inactivation center -- Variations 2 : stability of the inactive X -- Variations 3 : choice of active X -- The single active X -- Mosaicism -- Epimutations, chromatin disorders and sex differences in phenotype -- Determinants of female phenotypes
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| Subject
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X chromosome
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Mosaicism
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Genetic sex determination
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Sex-linkage (Genetics)
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Mosaicism
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X Chromosome Inactivation-- physiology
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| Subject
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Genetic Diseases, X-Linked
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| Subject
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Sex Factors
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| Dewey Classification
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616/.042
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| NLM classification
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QS 677
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