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" Rab GTPases "
edited by Guangpu Li, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma city, OK, USA, Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA.
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BL
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| Record Number
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615071
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| Doc. No
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dltt
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| Title & Author
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Rab GTPases : methods and protocols /\ edited by Guangpu Li, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma city, OK, USA, Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma, OK, USA.
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| Publication Statement
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New York :: Humana Press,, [2015]
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| Series Statement
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Methods in molecular biology,; 1298
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Springer protocols
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| ISBN
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9781493925681
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: 1493925687
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9781493925698
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1493925695
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Abstract
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This volume covers the latest technological advances in the characterization of the biosynthesis and functions of Rab GTPases and their regulation by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The book consists of 28 chapters, and starts with an overview of the Rab GTPase family. The next few chapters describe systematic approaches to the identification and classification of Rabs and Rab GAPs, as well as the detection of Rab isoprenylation and membrane distribution. The last few chapters examine the biochemical and functional properties of individual Rabs in the order of exocytic, recycling, and endocytic Rabs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Instructive and practical, Rab GTPases: Methods and Protocols approaches each topic with great detail and is a valuable resource for researchers and students interested in the field of Rab GTPases. --
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| Subject
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G proteins, Laboratory manuals.
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Guanosine triphosphatase, Laboratory manuals.
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rab GTP-Binding Proteins.
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GTPase-Activating Proteins.
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Guanine Nucleotide Exchange Factors.
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Protein Transport.
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| Added Entry
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Li, Guangpu, (Molecular biologist)
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