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" Kallikrein-related peptidases. "
Viktor Magdolen ... [et al.], editors.
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BL
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| Record Number
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616496
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dltt
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| Title & Author
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Kallikrein-related peptidases.\ Viktor Magdolen ... [et al.], editors.
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| Publication Statement
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Berlin :: Walter de Gruyter,, c2012.
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xvii, 409 p. :: ill.
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9783110260366 (alk. paper)
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9783110260373 (e-book)
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Genomic structure of the KLK locus -- Single nucleotide polymorphisms in the human KLK locus and their implication in various diseases -- Evolution of Kallikrein-related peptidases -- Structural aspects of Kallikrein-related peptidases -- Molecular recognition properties of Kallikrein-related peptidases on synthetic and endogenous substrates -- Natural, engineered, and synthetic inhibitors of Kallikrein-related peptidases -- Kallikrein-related peptidases as pharmaceutical targets -- Expression of Kallikrein-related peptidases under (patho) physiological conditions -- Kallikrein-related peptidases within the proteolytic web -- Kallikrein-Kinin cascade: bioregulation by human tissue kallikrein 1 (HK1, KLK 1) -- Role of KLK4 in dental enamel formation.
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Kallikrein-related peptidases and semen -- Kallikrein-related peptidases and inhibitors of the skin -- Physiological and pathophysiological roles of Kallikrein-related peptidases in the central nervous system -- Kallikrein-related peptidases (KLKS), proteinase-mediated signaling and proteinase-activated receptors (PARS) -- Pathophysiology of Kallikrein-related peptidases in lung cancer -- Clinical relevance of Kallikrein-related peptidases in gastric and colorectal cancer -- Pathophysiology of Kallikrein-related peptidases in head and neck cancer -- PSA (prostate-specific antigen) and other Kallikrein-related peptidases in prostate cancer -- Cellular model systems to study the tumor biological role of Kallikrein-related peptidases in ovarian and prostate cancer -- Clinical relevance of Kallikrein-related peptidases in breast cancer -- Clinical relevance of Kallikrein-related peptidases in ovarian cancer -- MicroRNAs : a new control mechanism for Kallikrein-related peptidases in kidney and other cancers -- Genomic instability of the KLK-locus in cancer -- Kallikrein-related peptidases as biomarkers in personalized cancer medicine.
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Kallikrein-- Genetics.
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Kallikrein-- Metabolism.
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Tumors-- Genetics.
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Proteolytic enzymes-- Metabolism.
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Magdolen, Viktor.
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ProQuest (Firm)
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