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" Forensic DNA typing : "
John M. Butler.
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BL
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| Record Number
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622147
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dltt
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| Main Entry
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Butler, John M., (John Marshall),1969-
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| Title & Author
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Forensic DNA typing : : biology, technology, and genetics of STR markers /\ John M. Butler.
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| Edition Statement
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2nd ed.
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| Publication Statement
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Amsterdam ;Boston :: Elsevier Academic Press,, c2005.
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| Page. NO
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xvii, 660 p. :: ill. (some col.) ;; 26 cm.
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| ISBN
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0121479528 (alk. paper)
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| Bibliographies/Indexes
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Includes bibliographical references and indexes.
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| Contents
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Overview and history of DNA typing -- DNA biology review -- Sample collection, DNA extraction and DNA quantitation -- The polymerase chain reaction (DNA amplification) -- Commonly used short tandem repeat markers and commercial kits -- Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates -- Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number -- Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics -- DNA separation methods : slab-gel and capillary electrophoresis -- DNA detection methods : fluorescent dyes and silver-staining -- Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems -- STR genotyping issues -- Laboratory validation -- New technologies, automation, and expert systems -- Combined DNA index system (CODIS) and the use of DNA databases -- Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification.
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DNA fingerprinting.
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Forensic genetics.
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DNA-- Synthesis.
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