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" Genetic control of malaria and dengue / "
edited by Zach N. Adelman
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BL
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| Record Number
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622593
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| Doc. No
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dltt
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| Title & Author
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Genetic control of malaria and dengue /\ edited by Zach N. Adelman
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| Page. NO
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xxvii, 457 pages :: illustrations ;; 24 cm
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| ISBN
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9780128002469
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: 0128002468
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Transgenic pests and human health: a short overview of social, cultural, and scientific considerations / Tim Antonelli, Amanda Clayton, Molly Hartzog, Sophia Webster and Gabriel Zilnik -- Concept and history of genetic control / Maxwell J. Scott and Mark Q. Benedict -- Considerations for disrupting malaria transmission in Africa using genetically modified mosquitoes, ecology of anopheline disease vectors, and current methods of control / Mamadou B. Coulibaly, Sekou F. Traoré and Yeya T. Touré -- Ecology of malaria vectors and current (nongenetic) methods of control in the Asia region / Patchara Sriwichai, Rhea Longley and Jetsumon Sattabongkot -- Ecology of Anopheles darlingi, the primary malaria vector in the Americas and current nongenetic methods of vector control / Jan E. Conn and Paulo E. Ribolla -- Considerations for disrupting dengue virus transmission; ecology of Aedes aegypti and current (nogenetic) methods of control / Roberto Barrera -- The challenge of disrupting vectorial capacity / Robert E. Sinden -- Gene insertion and deletion in mosquitoes / Zach N. Adelman, Sanjay Basu and Kevin M. Myles -- Gene drive strategies for population replacement / John M. Marshall and Omar S. Akbari -- Exploring the sex-determination pathway for control of mosquito-borne infectious diseases / James K. Biedler, Brantley A. Hall, Xioafang Jiang and Zhijian J. Tu -- Disruption of mosquito olfaction / Conor J. McMeniman -- Disruption of mosquito blood meal protein metabolism / Patricia Y. Scaraffia -- Engineering pathogen resistance in mosquitoes / Zach N. Adelman, Sanjay Basu and Kevin M. Myles -- Genetic control of malaria and dengue using wolbachia / Zhiyong Xi and Deepak Joshi -- Employing the mosquito microflora for disease control / Benjamin J. Blumberg, Sarah M. Short and George Dimopoulos -- Regulation of transgenic mosquitoes / Hector Quemada -- Economic analysis of genetically modified mosquito strategies / Eduardo A. Undurraga, Yara A. Halasa and Donald S. Shepherd -- Community engagement / Danilo O. Carvalho and Margareth L. Capurro -- Impact of genetic modification of vector populations on the malaria eradication agenda / Vanessa Macias and Anthony A. James
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| Abstract
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"Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; various strategies for altering the genome of mosquitoes in beneficial ways; strategies to translate basic knowledge of mosquito physiology and development into novel control efforts, and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This books is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown"--Back cover
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Malaria-- prevention control
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Malaria-- genetics
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Dengue-- prevention control
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Dengue-- genetics
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Culicidae-- genetics
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Insect Vectors-- genetics
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Mosquitoes as carriers of disease
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Mosquitoes-- Genetic engineering
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Malaria-- Prevention
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Dengue-- Prevention
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Vector control
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| Dewey Classification
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616.9/362
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| LC Classification
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QR201.M3.G46 2016
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| NLM classification
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2016 B-790
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WC 765
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| Added Entry
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Adelman, Zach N.
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