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" Epigenetic technological applications / "
edited by Y. George Zheng
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BL
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| Record Number
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622654
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| Doc. No
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dltt
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| Title & Author
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Epigenetic technological applications /\ edited by Y. George Zheng
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| Series Statement
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Translational epigenetics series
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| Page. NO
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xxiii, 491 pages, 18 unnumbered pages of plates :: illustrations (some color) ;; 25 cm
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| ISBN
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9780128010808
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: 0128010800
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index
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| Subject
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Epigenetics-- Data processing
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| Subject
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Epigenetics-- Research-- Methodology
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| Subject
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Epigenomics
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| Dewey Classification
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572.8/65
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| LC Classification
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QH450.E6535 2015
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| Added Entry
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Zheng, Y. George,1970-
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