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" The epigenome and developmental origins of health and disease / "
edited by Cheryl S. Rosenfeld
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BL
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| Record Number
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622677
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dltt
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| Title & Author
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The epigenome and developmental origins of health and disease /\ edited by Cheryl S. Rosenfeld
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| Page. NO
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xvii, 542 pages :: illustrations (chiefly color) ;; 24 cm
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| ISBN
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9780128013830
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: 0128013834
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9780128016725
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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The developmental origins of health and disease (DOHaD) concept : past, present, and future / Peter D. Gluckman, Tatjana Buklijas and Mark A. Hanson -- Historical perspective of developmental origins of health and disease in humans / Lewis P. Rubin -- DOHaD and the periconceptional period, a critical window in time / Congshan Sun, Miguel A. Velazquez and Tom P. Fleming -- Introduction to epigenetic mechanisms : the probable common thread for various developmental origins of health and diseases effects / Martha Susiarjo -- Perinatal neurohormonal programming and endocrine disruption / Cheryl S. Rosenfeld -- Parental nutrition and developmental origins of health and disease / Miguel A. Velazquez, Congshan Sun and Tom P. Fleming -- Maternal prenatal stress and the developmental origins of mental health : the role of epigenetics / Kieran J. O'Donnell and Vivette Glover -- Epigenetics in the developmental origin of cardiovascular disorders / Jeffrey S. Gilbert -- Developmental effects of endocrine-disrupting chemicals in the ovary and on female fertility / Mehmet Uzumcu and Aparna Mahakali Zama -- Developmental and eipigenetic origins of male reproductive pathologies / Carlos Guerrero-Bosagna -- Developmental origins of childhood asthma and allergic conditions : is there evidence of epigenetic regulation? / Steve Turner -- Immune disorders, epigenetics, and the developmental origins of health and disease / Rodney R. Dietert and Amrie C. Grammer -- Neurobehavioral disorders and developmental origins of health and disease / Curt A. Sandman, Quetzal A. Class, Laura M. Glynn and Elysia Poggi Davis -- Metabolic disorders and developmental origins of health and disease / Sara E. Pinney --
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The developmental origins of renal dysfunction / James S.M. Cuffe, Sarah L. Walton and Karen M. Moritz -- Cancer and developmental origins of health and disease : epigenetic reprogramming as a mediator / Shuk-Mei Ho, Ana Cheong, Sarah To, Vinothini Janakiram, Pheruza Tarapore and Yuet-Kin Leung -- Epigenetic regulation of gastrointestinal epithelial barrier and developmental origins of health and disease / J.P. Lallès, C. Michel, V. Theodorou and J.P. Segain -- How the father might epigenetically program the risk for developmental origins of health and disease effects in his offspring / Kristin E. Murphy, Timothy G. Jenkins and Douglas T. Carrell -- Linkage between in utero environmental changes and preterm birth / Markus Velten and Lynette K. Rogers -- Sexual dimorphism and DOHaD through the lens of epigenetics : genetic, ancestral, developmental, and environmental origins from previous to the next generation(s) / Claudine Junien, Sara Fneich, Polina Panchenko, Sarah Voisin and Anne Gabory -- Transgenerational epigenetic inheritance : past exposures, future diseases / Carlos Guerrero-Bosagna -- The placenta and developmental origins of health and disease / Jane K. Cleal and Rohan M. Lewis -- The moral and legal relevance of DOHaD effects for pregnant mothers / Michele Loi and Marianna Nobile -- Introduction to Moms in Motion (MIM) / Cheryl S. Rosenfeld -- Reversing harmful developmental origins of health and disease effects / Mei-Wei Chang, Susan Nitzke, Roger Brown, M Jean Brancheau Egan, Kobra Eghtedary and Cheryl S. Rosenfeld -- Informational resources for developmental origins of health and disease research / Cheryl S. Rosenfeld
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| Abstract
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"The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or conversely promote the health of the offspring. This book mines the existing literature of a variety of disciplines, from toxicology to nutrition to epigenetics, to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother's diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, and neurobehavioral disorders, and increased risk of cancer, to list but a few examples. Importantly, the common thread of how in utero and postnatal environmental changes may lead to DOHaD effects is through various epigenetic changes. The Epigenome and Developmental Origins of Health and Disease is a unique resource not only for geneticists and epigeneticists, but also for toxicologists, obestetricians, gynecologists, neurobiologists, nutritionists, physiologists, and psychologists."--Page 4 of cover
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| Subject
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Epigenetics
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Developmental biology
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Diseases-- Causes and theories of causation
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Medical genetics
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Human genome
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Disease susceptibility
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Developmental Biology
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Epigenesis, Genetic
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Disease Susceptibility
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Embryology
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Genome, Human
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Prenatal Exposure Delayed Effects
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| Dewey Classification
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599.935
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| LC Classification
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QH450.E6585 2016
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| NLM classification
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QU 475
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| Added Entry
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Rosenfeld, Cheryl S.
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