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" Regulated cell death Part B : "
edited by Avi Ashkenazi, James A. Wells, Junying Yuan
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BL
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| Record Number
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622688
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dltt
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| Title & Author
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Regulated cell death Part B : : necroptotic, autophagic and other non-apoptotic mechanisms /\ edited by Avi Ashkenazi, James A. Wells, Junying Yuan
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| Series Statement
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Methods in enzymology,; v.545
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| Page. NO
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xiii, 337 pages, 26 unnumbered pages of plates :: illustrations (some color) ;; 24 cm
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| ISBN
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9780128014301
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: 012801430X
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| Bibliographies/Indexes
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Includes bibliographical references and indexes
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| Contents
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Assays for necroptosis and activity of RIP kinases -- IAP family of cell death and signaling regulators -- Activation of the NLRP3 inflammasome by proteins that signal for necroptosis -- Characterization of the ripoptosome and its components: implications for anti-imflammatory and cancer therapy -- Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members -- Necrotic cell death in caenorhabditis elegans -- Noncanonical cell death in the nematode caenorhabditis elegans -- Autophagy and cell death in the fly -- Structural studies of death receptors -- Use of E2 ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins -- Multidimensional profiling in the investigation of small-molecule-induced cell death
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| Abstract
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Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field
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| Subject
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Cell death
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Autophagic vacuoles
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Ashkenazi, Avi
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Yuan, Junying
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Wells, Jim
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