|
" Vaccine analysis : "
Brian K. Nunnally, Vincent E. Turula, Robert D. Sitrin, editors
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
650468
|
| Doc. No
|
:
|
dltt
|
| Title & Author
|
:
|
Vaccine analysis : : strategies, principles, and control /\ Brian K. Nunnally, Vincent E. Turula, Robert D. Sitrin, editors
|
| Page. NO
|
:
|
1 online resource (xii, 665 pages) :: illustrations (some color)
|
| ISBN
|
:
|
3662450240
|
|
|
:
|
: 9783662450246
|
|
|
:
|
9783662450239
|
| Bibliographies/Indexes
|
:
|
Includes bibliographical references and index
|
| Contents
|
:
|
Live Attenuated Viral Vaccines -- Inactivated Viral Vaccines -- Recombinant Virus Like Particle Protein Vaccines -- Analysis of influenza vaccines -- Live-attenuated and inactivated whole-cell bacterial vaccines -- Analytical control strategy of bacterial subunit vaccines -- Bacterial Polysaccharide Vaccines: Analytical Perspectives -- Glycoconjugate vaccines -- Vaccines in research and development: new production platforms and new biomolecular entities for new needs -- Role of Analytics In Viral Safety -- Deep Sequencing Applications for Vaccine Development and Safety -- Quality-by-design: As related to analytical concepts, control and qualification -- Vaccine Potency Assays -- Establishing a Shelf-life and Setting Lot-release Specifications -- Vaccine Reference Standards -- Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements -- Dendritic cell targeting vaccines
|
| Abstract
|
:
|
This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure
|
| Subject
|
:
|
Chemistry, Analytic.
|
| Subject
|
:
|
Vaccines industry-- Quality control.
|
| Subject
|
:
|
Vaccines-- Testing.
|
| Subject
|
:
|
Biomedicine.
|
| Subject
|
:
|
Medical Biochemistry.
|
| Subject
|
:
|
Vaccine.
|
| Dewey Classification
|
:
|
615/.372
|
| LC Classification
|
:
|
QR189.V33 2015
|
| Added Entry
|
:
|
Nunnally, Brian K.
|
|
|
:
|
Sitrin, Robert D.
|
|
|
:
|
Turula, Vincent E.
|
| Added Entry
|
:
|
Ohio Library and Information Network.
|
| |