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" Mass spectrometry for drug discovery and drug development / "
edited by Walter A. Korfmacher.
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BL
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| Record Number
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658090
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dltt
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| Title & Author
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Mass spectrometry for drug discovery and drug development /\ edited by Walter A. Korfmacher.
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| Series Statement
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Wiley series on mass spectrometry.
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| Page. NO
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xii, 461 pages :: illustrations ;; 26 cm.
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| ISBN
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9780470942383 (cloth)
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: 047094238X (cloth)
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gerard Hopfgartner -- 2. Utility of high resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendraÿ N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark Cancilla and Mike Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high resolution full scan? / Lieve Dillen and Filip Cuyckens.
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| Subject
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Drugs-- Analysis.
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Drug development.
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Mass spectrometry.
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Drug Discovery.
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Mass Spectrometry-- methods.
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Peptides-- analysis.
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Pharmaceutical Preparations-- analysis.
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Proteins-- analysis.
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| Dewey Classification
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615.1/9
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| LC Classification
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RM301.25.M37 2013
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| NLM classification
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2013 C-902
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QV 745
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| Added Entry
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Korfmacher, Walter A.
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