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" Protective groups in organic synthesis "
Document Type
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BL
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Record Number
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658226
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Doc. No
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dltt
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Main Entry
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Greene, Theodora W., (Theodora Whatmough),1931-2005
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Title & Author
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Protective groups in organic synthesis
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Edition Statement
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Third edition // Theodora W. Greene and Peter G.M. Wuts
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Publication Statement
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New York :: Wiley,, c1999
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Page. NO
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xxi, 779 p. :: ill. ;; 25 cm
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ISBN
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0471160199 (cloth : acid-free paper)
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: 9780471160199 (cloth : acid-free paper)
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Notes
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"A Wiley-Interscience publication."
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Bibliographies/Indexes
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Includes bibliographical references and index
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Contents
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The Role of Protective Groups in Organic Synthesis -- Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols -- Protection for Phenols and Catechols -- Protection for the Carbonyl Group -- Protection for the Carboxyl Group -- Protection for the Thiol Group -- Protection for the Amino Group -- Protection for the Alkyne-CH -- Protection for the Phosphate Group -- Reactivities, Reagents, and Reactivity Charts
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Abstract
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This edition provides readers with a comprehensive compendium of 1,050 of the most useful protective groups as well as 5,350 references to original publications. Protective groups are organized by six major organic functional groups: hydroxyl, amino, carboxyl, carbonyl, sulfhydryl, and phosphate groups (the last new to this edition). Also added in this edition are protection of the alkyne-CH, expanded coverage of protection of all groups, and many new enzymatic methods of protection and deprotection. Each chapter briefly describes the classes of available protective groups, followed by an in-depth look at the chemistry of individual protective groups, their properties, and the best methods of formation and cleavage. Ten reactivity charts with more than 28,000 entries summarize the relative reactivities of 270 commonly used protective groups with 108 reagents
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Subject
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Organic compounds-- Synthesis
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Subject
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Protective groups (Chemistry)
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LC Classification
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QD262.G665 1999
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Added Entry
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Wuts, Peter G. M
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