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" Drug discovery research : "
edited by Ziwei Huang
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BL
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| Record Number
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658363
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| Doc. No
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dltt
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| Title & Author
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Drug discovery research : : new frontiers in the post-genomic era /\ edited by Ziwei Huang
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| Publication Statement
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Hoboken, N.J. :: Wiley-Interscience,, c2007
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| Page. NO
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xix, 521 p., [16] p. of plates :: ill. (some col.) ;; 25 cm
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| ISBN
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9780471672005 (cloth)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Molecular docking and structure-based design / P. Therese Lang ... [et al.] -- Recent advances in drug discovery research using structure-based virtual screening techniques : examples of success for diverse protein targets / Sutapa Ghosh ... [et al.] -- Virtual screening in drug discovery / Malcolm J. McGregor, Zhaowen Luo, and Xuliang Jiang -- Computer-aided drug design / Grace Shiahuy Chen and Ji-Wang Chern -- Focused library design based on hit and target structures : method and application in drug discovery / Weiliang Zhu ... [et al.] --
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Beyond natural products : synthetic analogs of bryostatin 1 / Paul A. Wender ... [et al.] -- The promises and pitfalls of small-molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG) / Amanda C. Nottbohm and Paul J. Hergenrother -- Cyclic ADP-ribose analogues with minimal structure : synthesis and calcium-release activity / Lihe Zhang and Andreas H. Guse -- Evaluation of neuroimmunophilin ligands / Junhai Xiao, Aihua Nie, and Song Li -- Chiral drugs and the associated asymmetric synthesis / Jiange Zhang and Guoqiang Lin --
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Alpha-helix mimetics in drug discovery / Hang Yin, Gui-In Lee, and Andrew D. Hamilton -- Basic and translational research of chemokine ligands and receptors and development of novel therapeutics / Won-Tak Choi ... [et al.] -- Research progress in protein post-translational modification / Jia Hu, Yanting Guo, and Yanmei Li -- Controlled release of antibiotics encapsulated in nanoporous sol-gel materials with tunable pore parameters / Houping Yin, Laura Zheng, and Yen Wei -- Retinoic acid and arsenic trioxide treatment in acute promyelocytic leukemia : a model of oncoprotein targeted therapy / Jian-Hua Tong, Sai-Juan Chen, and Zhu Chen
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2-chlorodeoxyadenosine (cladribine) : rational development of a novel chemotherapeutic agent / Howard B. Cottam and Dennis A. Carson -- Apoptosis-based drug discovery for cancer / John C. Reed ... [et al.] -- Mechanism-based development of memantine as a therapeutic agent in treating Alzheimer's disease and other neurologic disorders : low-affinity, uncompetitive antagonism with fast off-rate / Huei-Sheng Vincent Chen and Stuart A. Lipton -- Bridging bench to clinic : roles of animal models for post-genomics drug discovery on metabolic diseases / Chi-Wai Wong and Ling Chen -- Stem cell research and applications for human therapies / Prithi Rajan ... [et al.]
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| Subject
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Drugs-- Design
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Biopharmaceutics
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Pharmaceutical chemistry
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| LC Classification
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RS420.D83 2007
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RS420.D83 2007
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| Added Entry
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Huang, Ziwei,1965-
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