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" Fundamentals of early clinical drug development : "
edited by Ahmed F. Abdel-Magid and Stéphane Caron
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BL
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| Record Number
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658371
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| Doc. No
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dltt
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| Title & Author
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Fundamentals of early clinical drug development : : from synthesis design to formulation /\ edited by Ahmed F. Abdel-Magid and Stéphane Caron
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| Publication Statement
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Hoboken, N.J. :: Wiley-Interscience,, c2006
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| Page. NO
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xv, 323 p. :: ill. ;; 25 cm
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| ISBN
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0471692786 (cloth)
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: 9780471692782
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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Reflections on process research II / Edward J.J. Grabowski -- Development and scale-up of a heterocyclic cross-coupling for the synthesis of 5-(2-(3-methyl-3H-imidazol-4-yl)thieno(3,2-b)pyridin-7-yl)amino-2-methyl-1H-indol / John A. Ragan -- Large-scale enantioselective preparation of 2E,7E, 5S,6R, 5-hydroxy-6-methyl-8-phenyl-octa-2,7-dienoic acid, a key fragment for the formal total synthesis of the anti-tumor agent cryptophycin 52 / James Aikins ... [et al.] -- Efforts toward a commercially viable route and process to the synthesis of HIV PI GW640385X / John C. Roberts ... [et al.] -- Development of an asymmetric synthesis of ABT-100 / Albert W. Kruger ... [et al.] -- Asymmetric hydrogenation: a new route to pregabalin / Rex Jennings ... [et al.] -- Responsibilities of the process chemist: beyond synthetic organic chemistry / Stéphane Caron -- Outsourcing: the challenge of science, speed, and quality / Simone Andler-Burzlaff, Jason Bertola, and Roger E. Marti -- Automation and the changing face of process research in the pharmaceutical industry / Edward J. Delaney ... [et al.] -- Large scale synthesis: an engineering perspective / Joseph H. Childers, Jr. -- Synthesis and application of radioisotopes in pharmaceutical research and development / Larry E. Weaner and David C. Hoerr -- Selection of the drug form in exploratory development / George J. Quallich -- Strategies to control particle size of active pharmaceutical ingredients / David J. am Ende and Peter R. Rose -- Challenges in early formulation: turning drug substance into drug product / Mark H. Kleinman and Beeah Lee -- Intellectual property and early development / Maria I. Shchuka
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| Subject
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Clinical pharmacology
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Pharmaceutical technology
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Drugs-- Testing
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| Dewey Classification
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615/.1
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| LC Classification
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RM301.27.F86 2006
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RM301.27.F86 2006
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| NLM classification
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QV 744F981 2006
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| Added Entry
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Abdel-Magid, Ahmed F.,1947-
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Caron, Stéphane
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