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" Therapeutic nanomaterials / "
edited by Mustafa O. Guler, Ayse B. Tekinay
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BL
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662463
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dltt
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Therapeutic nanomaterials /\ edited by Mustafa O. Guler, Ayse B. Tekinay
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1 online resource
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| ISBN
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9781118987483
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: 1118987489
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9781118987469
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1118987462
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9781118987476
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1118987470
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9781118987452 (cloth)
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Includes bibliographical references and index
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| Contents
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Nanomaterials for Medicine / Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- Nanoscale Material Properties -- Nanomaterials for Understanding Disease Pathways -- Nanomaterials for Therapy -- Challenges and Future Prospects -- Nanosized Delivery Systems for Tissue Regeneration / Goksu Cinar, Didem Muncuoglu, Ayse B. Tekinay, Mustafa O. Guler -- Introduction -- Delivery of Protein Therapeutics with Nanocarriers for Tissue Regeneration -- GFs and Cytokines -- Gene and siRNA Delivery with Nanocarriers for Tissue Regeneration -- Gene Delivery -- SIRNA Delivery -- Systemic Targeting and Cellular Internalization Strategies for Tissue Regeneration -- Targeted Delivery -- Cellular Internalization Strategies -- Future Perspectives -- References -- Nanomaterials for Neural Regeneration / Melike Sever, Busra Mammadov, Mevhibe Gecer, Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- Extracellular Matrix of Central Nervous System -- ECM of Peripheral Nervous System -- Urgent Need for Materials to Induce Regeneration in Nervous Tissue -- Nanomaterials for Neural Regeneration -- Physical Functionalization of Nanomaterials to Induce Neural Differentiation -- Effects of Mechanical Stiffness on Cellular Behavior -- Effects of Dimensionality on Cellular Behavior -- Effects of Substrate Topography on Cell Behavior -- Effects of Electrical Conductivity OD Cell Behavior -- Chemical and Biological Functionalization of Nanomaterials for Neural Differentiation -- Effects of Biologically Active Molecules on Cell Behavior -- Effects of Chemical Groups on Cellular Behavior -- Effects of Biofunetionalization on Cellular Behavior Through ECM-Derived Short Peptides -- Conclusion -- References -- Therapeutic Nanomaterials for Cartilage Regeneration / Elif Arslan, Seller Ustun Yaylaci, Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- Current Treatment Methods for Cartilage Injuries -- Tissue Engineering Efforts -- Natural Polymers -- Synthetic Polymers -- Composite Materials -- Physical Stimuli -- Clinical Therapeutics for Cartilage Regeneration -- Conclusions and Future Perspectives -- References -- Wound Healing Applications of Nanomaterials / Berna Senturk, Gozde Uzunalli, Rashad Mammadov, Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- The Structure of Healthy Mammalian Skin -- The Mechanisms of Wound Healing -- Repair Process in Chronic Wounds -- Applications of Nanomaterials for the Enhancement of Wound Healing Process -- Artificial Skin -- Natural Nanomaterials for Wound Healing -- Synthetic Nanomaterials for Wound Healing -- Wound Dressings Containing Growth Factors -- Biomimetic Materials -- Current Challenges in the Design of Nanomaterials for Chronic Wound Management -- Peptide Nanofiber Gels for Wound Healing -- Relevance of Nanofibrous Structure of Peptide Gels for Wound Healing -- Engineered PA Nanofiber Gels for Wound Healing and Insights into Various Designs -- References -- Nanomaterials for Bone Tissue Regeneration and Orthopedic Implants / Gulcihan Gulseren, Melis Goktas, Hakan Ceylan, Ayse B. Tekinay, Mustafa O. Guler -- Introduction -- Bone Matrix -- Organic Matrix and Bioactivity -- Inorganic Matrix, Mineralization, and Bone Organization -- Mechanical Properties and Structural Hierarchy of Bone Tissue -- Regulation of Bone Matrix in Adult Tissue -- Angiogenic Factors in Bone Remodeling -- Strategies for Bone Tissue Regeneration -- Hard Grafts for Bone Regeneration -- Soft Grafts for Bone Regeneration -- Peptide-Based Bone Grafts -- Polymer Nanocomposites as Bone Grafts -- Future Perspectives -- References -- Nanomaterials for the Repair and Regeneration of Dental Tissues / Gulistan Tansik, Alper Devrim Ozkan, Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- Formation of Dental and Osseous Tissues -- Dental Implants -- Metallic Implants -- Ceramic Implants -- Polymeric Implants -- Osseoiintegration of Dental Implants -- Uses of Nanotechnology in the Development of Dental Implants -- Enhancement of the Osseointegration Process -- Pulp and Dentin Tissue Regeneration -- Whole Tooth Regeneration -- Conclusions and Future Perspectives -- References -- Nanomaterials as Tissue Adhesives / I. Ceren Yasa, Hakan Ceylon, Ayse B. Tekinay, Mustafa O. Guler -- Introduction -- Tissue Adhesives Based on Synthetic Polymers -- Naturally Derived Tissue Adhesives -- Bioinspired Strategies -- Nanoenabled Adhesives -- Conclusion and Future Prospects -- References -- Advances in Nanoparticle-Based Medical Diagnostic and Therapeutic Techniques / Melis Sardan, Alper Devrim Ozkan, Aygul Zengin, Ayse B. Tekinay, Mustafa O. Guler -- Introduction -- NPs used in MRI -- T₁CAs -- T₂CAs -- Dual Modal Contrast Agents -- NPs used in Computed Tomography -- Noble Metal-Based NPs -- Heavy Metal-Based NPs -- NPs used in Optical and Fluorescence Imaging -- Quantum Dots -- AuNPs -- UCNPs -- Theranostic Approaches and Multimodal Systems -- Overlook and Future Directions -- References -- Biosensors for Early Disease Diagnosis / Ahmet E. Topal, Alper Devrim Ozkan, Aykutlu Dana, Ayse B. Tekinay, Mustafa O. Guler -- Introduction -- Biosensor Elements -- Recognition Elements -- Output Type and Detection Techniques -- Optical Biosensors -- Electrical and Electrochemical Biosensors -- Mechanical Biosensors -- Other Biosensor Types -- The Impact of Nanotechnology and Nanomaterials in Biosensor Design -- Early Diagnosis and Biosensor-Based Disease Detection -- Conclusion and Future Directions -- References -- Safety of Nanomaterials / Nuray Gunduz, Elif Arslan, Mustafa O. Guler, Ayse B. Tekinay -- Introduction -- Characterization, Design, and Synthesis of Nanomaterials -- Chemical Identity and Physicochemical Properties -- Biological Identity -- Interactions at the Cell-Material Interface -- Intracellular Activity -- Cellular Uptake Mechanisms -- Assays for Cell Viability/Proliferation -- Assays for Oxidative Stress and Apoptosis Mechanisms -- Evaluation of Uptake and Accumulation of ENMs -- Genotoxicity Assays -- Animal Models and Long-Term Risk Assessment -- The Blood-Brain Barrier -- Conclusions and Future Perspectives -- References
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| Subject
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Nanostructured materials-- Therapeutic use.
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| Subject
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Medical technology.
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| Dewey Classification
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610.28
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| LC Classification
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R857.N34
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| Added Entry
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Güler, Mustafa Ö.,1978-
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Tekinay, Ayse B.
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Ohio Library and Information Network.
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