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" Genome instability in cancer development / "
edited by Erich A. Nigg.
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BL
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| Record Number
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663422
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dltt
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| Title & Author
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Genome instability in cancer development /\ edited by Erich A. Nigg.
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| Series Statement
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Advances in experimental medicine and biology ;; v. 570
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| Page. NO
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xv, 511 pages :: illustrations (some color) ;; 26 cm.
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| ISBN
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1402037635 (hbk.)
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: 1402037643 (ebook)
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: 9781402037634 (hbk.)
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: 9781402037641 (ebook)
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| Bibliographies/Indexes
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Includes bibliographical references and index
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| Contents
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The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao
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| Subject
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Cancer-- Genetic aspects.
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Genomics.
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DNA Repair.
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Genomic Instability.
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Mutation.
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Neoplasms-- etiology.
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Neoplasms-- genetics.
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| Added Entry
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Nigg, Erich A.
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Ohio Library and Information Network.
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