|
" The toxic induction of irritant asthma, irritant rhinitis, and related conditions / "
William J. Meggs, editor
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
667506
|
| Doc. No
|
:
|
dltt
|
| Title & Author
|
:
|
The toxic induction of irritant asthma, irritant rhinitis, and related conditions /\ William J. Meggs, editor
|
| Page. NO
|
:
|
1 online resource
|
| ISBN
|
:
|
9781461490449
|
|
|
:
|
: 1461490448
|
|
|
:
|
9781461490432
|
|
|
:
|
146149043X
|
| Bibliographies/Indexes
|
:
|
Includes bibliographical references and index
|
| Contents
|
:
|
Introduction: Irritant asthma, irritant rhinitis -- Airway Anatomy, Physiology, and Inflammation -- Reactive Airways Dysfunction Syndrome (RADS) and Irritant-Induced Asthma -- Acute Toxicity of Respiratory Irritant Exposures -- Particulate Exposure and Cardiovascular Inflammation -- Products of Combustion -- Irritant and Airborne Contact Dermatitis -- Exposure Limits -- Occupational Issues Related to Respiratory Irritants -- The Brain as a Target Organ for Allergic and Irritant Sensitivity: A Review and Suggestions for Research -- An Approach to Treating Irritant Airway Inflammation -- Summary and Research Needs -- Index
|
| Abstract
|
:
|
Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals. This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions
|
| Subject
|
:
|
Asthma.
|
| Subject
|
:
|
Rhinitis.
|
| Subject
|
:
|
Nose-- Diseases.
|
| Dewey Classification
|
:
|
616.2/12
|
| LC Classification
|
:
|
RF341.T69 2013eb
|
| Added Entry
|
:
|
Meggs, William Joel
|
| Added Entry
|
:
|
Ohio Library and Information Network.
|
| |