| Document Type
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BL
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| Record Number
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668853
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| Doc. No
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dltt
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| Title & Author
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Platelet function : : assessment, diagnosis, and treatment /\ edited by Martin Quinn, Desmond Fitzgerald.
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| Publication Statement
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Totowa, N.J. :: Humana Press,, c2005.
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| Series Statement
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Contemporary cardiology (Totowa, N.J.)
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| Page. NO
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xi, 397 p. :: ill. ;; 24 cm.
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| ISBN
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1588292444 (alk. paper)
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: 9781588292445 (alk. paper)
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: 1592599176 (e-ISBN)
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: 9781592599172 (e-ISBN)
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Platelet physiology / Martin Quinn -- Platelet integrins and signaling / Karlheinz Peter -- Platelet adhesion / Brian Savage and Zaverio M. Ruggeri -- Structure-function of the platelet cytoskeleton / Elaine L. Bearer -- Platelets and inflammation / Meinrad Gawaz -- Platelet signal-dependent protein synthesis / Stephan Lindemann ... [et al.] -- Phosphoproteomics of human platelets / Katrin Marcus and Helmut E. Meyer -- Platelet function studies / Dermot Cox -- Platelet function under flow / José A. López, Ian del Conde, and Jing-Fei Dong -- Pharmacodynamics of GPIIb-IIIa receptor blockade / Lisa K. Jennings and Melanie M. White -- Prostanoid generation in platelet function: assessment and clinical relevance / Bianca Rocca and Carlo Patrono -- Platelets and prothrombin / Michael Kalafatis ... [et al.] -- Markers of platelet activation and granule secretion / Alan D. Michelson and Mark I. Furman -- Genomic and proteomic analysis of platelets: clinical applications / Andrew Maree and James McRedmond -- Antiplatelet agents / Jacqueline Saw and David J. Moliterno -- Assessing platelet function in clinical trials / Neil Kleiman.
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| Abstract
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A cutting-edge review of the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed.
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| Subject
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Blood platelet disorders-- Diagnosis.
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| Subject
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Blood platelets-- Examination.
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| Subject
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Blood Platelets-- physiology.
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Blood Platelet Disorders-- diagnosis.
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| Subject
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Blood Platelet Disorders-- physiopathology.
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| Subject
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Blood Platelet Disorders-- therapy.
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| Dewey Classification
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616.1/57
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| LC Classification
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RC647.B5P564 2005
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| NLM classification
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2005 K-428
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WH 600P716 2005
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| Added Entry
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Quinn, Martin,1968-
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Fitzgerald, Desmond,1953-
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