|
" Chemical library design "
edited by Joe Zhongxiang Zhou.
| Document Type
|
:
|
BL
|
| Record Number
|
:
|
682984
|
| Doc. No
|
:
|
b505173
|
| Title & Author
|
:
|
Chemical library design\ edited by Joe Zhongxiang Zhou.
|
| Publication Statement
|
:
|
New York, NY :: Humana Press,, c2011.
|
| Series Statement
|
:
|
Methods in molecular biology,; 685
|
|
|
:
|
Springer protocols
|
| ISBN
|
:
|
160761930X
|
|
|
:
|
: 1607619318
|
|
|
:
|
: 9781607619307
|
|
|
:
|
: 9781607619314
|
| Bibliographies/Indexes
|
:
|
Includes bibliographical references and index.
|
| Contents
|
:
|
Historical overview of chemical library design / Roland E. Dolle -- Chemoinformatics and library design / Joe Zongxiang Zhou -- Molecular library design using multi-objective optimization methods / Christos A. Nicolaou and Christos C. Kannas -- A scalable approach to combinatorial library design / Puneet Sharma, Srinivasa Salapaka, and Carolyn Beck -- Application of Free-Wilson selectivity analysis for combinatorial library design / Simone Sciabola ... [et al.] -- Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design / Jerry O. Ebalunode, Weifan Zheng, and Alexander Tropsha -- Combinatorial library design from reagent pharmacophore fingerprints / Hongming Chen, Ola Engkvist, and Niklas Blomberg -- Docking methods for structure-based library design / Claudio N. Cavasotto and Sharangdhar S. Phatak -- Structure-based library design in efficient discovery of novel inhibitors / Shunqi Yan and Robert Selliah -- Structure-based and property-compliant library design of 11[beta]-HSD1 adamantyl amide inhibitors / Genevieve D. Paderes ... [et al.] -- Design of screening collections for successful fragment-based lead discovery / James Na and Qiyue Hu -- Fragment-based drug design / Eric Feyfant ... [et al.] -- LEAP into the Pfizer Global Virtual Library (PGVL) space : creation of readily synthesizable design ideas automatically / Qiyue Hu ... [et al.] -- The design, annotation, and application of a kinase-targeted library / Hualin Xi and Elizabeth A. Lunney -- PGVL hub : an integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds / Zhengwei Peng ... [et al.] -- Design of targeted libraries against the human Chk1 kinase using PGVL hub / Xengwei Peng and Qiyue Hu -- GLARE : a tool for product-oriented design of combinatorial libraries / Jean-François Truchon -- CLEVER : a general design tool for combinatorial libraries / Tze Hau Lam ... [et al.].
|
| Subject
|
:
|
Cheminformatics.
|
| Subject
|
:
|
Combinatorial chemistry.
|
| Subject
|
:
|
Drugs-- Design.
|
| Subject
|
:
|
Combinatorial Chemistry Techniques-- methods.
|
| Subject
|
:
|
Small Molecule Libraries.
|
| Subject
|
:
|
Drug Discovery-- methods.
|
| Subject
|
:
|
Medical Informatics-- methods.
|
| Subject
|
:
|
Pharmaceutical Preparations-- chemistry.
|
| Added Entry
|
:
|
Zhou, Joe Zhongxiang.
|
| |